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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intravenous immunoglobulin (IVIG) vs corticosteroids
Intensive care unit (ICU) length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs corticosteroids
Time to complete re‐epithelialisation ‐ not reported · treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs corticosteroids
Intensive care unit (ICU) length of stay ‐ not reported · treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs corticosteroids
Total hospital length of stay ‐ not reported · treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs no corticosteroids
Intensive care unit (ICU) length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs corticosteroids
Adverse effects leading to discontinuation of SJS/TEN therapy ‐ not reported (see comments) · treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs corticosteroids
Disease‐specific mortality ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs corticosteroids
Time to complete re‐epithelialisation ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs corticosteroids
Total hospital length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs corticosteroids
Adverse effects leading to discontinuation of SJT/TEN therapy ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs corticosteroids
Intensive care unit (ICU) length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs intravenous immunoglobulin (IVIG)
Disease‐specific mortality ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs intravenous immunoglobulin (IVIG)
Time to complete re‐epithelialisation ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs intravenous immunoglobulin (IVIG)
Intensive care unit (ICU) length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs intravenous immunoglobulin (IVIG)
Total hospital length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs no corticosteroids
Total hospital length of stay – not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs intravenous immunoglobulin (IVIG)
Adverse effects leading to discontinuation of SJS/TEN therapy ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs intravenous immunoglobulin (IVIG)
Time to complete re‐epithelialisation ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs intravenous immunoglobulin (IVIG)
Total hospital length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs intravenous immunoglobulin (IVIG)
Adverse effects leading to discontinuation of SJT/TEN therapy ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Cyclosporin vs intravenous immunoglobulin (IVIG)
Intensive care unit (ICU) length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs cyclosporin
Disease‐specific mortality ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs cyclosporin
Time to complete re‐epithelialisation ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs cyclosporin
Intensive care unit (ICU) length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs cyclosporin
Total hospital length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs no corticosteroids
Adverse effects leading to discontinuation of SJS/TEN therapy – not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Etanercept vs cyclosporin
Adverse effects leading to discontinuation of SJS/TEN therapy ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Intravenous immunoglobulin (IVIG) vs no IVIG
Intensive care unit (ICU) length of stay ‐ not reported · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome
Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN),… (2022) · Cochrane
no estimate extractedNRNo studies
Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only
ADHD symptoms · people with ADHD and epilepsy
Stimulant and non‐stimulant drug therapy for people with attention deficit hyperactivity disorder and epilepsy (2022) · Cochrane
no estimate extractedNRNo studies
Osmotic‐release oral system methylphenidate vs placebo
Proportion of people experiencing 50% or greater reduction in seizure frequency · people with ADHD and epilepsy
Stimulant and non‐stimulant drug therapy for people with attention deficit hyperactivity disorder and epilepsy (2022) · Cochrane
no estimate extractedNRNo studies
Omega‐3 (with risperidone and previous ASM) vs risperidone and previous ASM only
Seizure severity · people with ADHD and epilepsy
Stimulant and non‐stimulant drug therapy for people with attention deficit hyperactivity disorder and epilepsy (2022) · Cochrane
no estimate extractedNRNo studies
Ocrelizumab vs placebo
Number of participants with gadolinium‐enhancing T1 lesions on MRI · people with primary progressive multiple sclerosis
Ocrelizumab for multiple sclerosis (2022) · Cochrane
no estimate extractedNRNo studies
Ocrelizumab vs placebo
Number of participants with new or enlarging T2‐hyperintense lesions on MRI · people with primary progressive multiple sclerosis
Ocrelizumab for multiple sclerosis (2022) · Cochrane
no estimate extractedNRNo studies
14 days on/off antibiotic regimen vs 28 days on/off antibiotic regimen
Exacerbation frequency · people with bronchiectasis
Intermittent prophylactic antibiotics for bronchiectasis (2022) · Cochrane
no estimate extractedNRNo studies
14 days on/off antibiotic regimen vs 28 days on/off antibiotic regimen
Frequency of hospital admissions for pulmonary exacerbations ‐ not measured · people with bronchiectasis
Intermittent prophylactic antibiotics for bronchiectasis (2022) · Cochrane
no estimate extractedNRNo studies
14 days on/off antibiotic regimen vs 14 days on/off placebo regimen
Frequency of hospital admissions for pulmonary exacerbations ‐ not measured · people with bronchiectasis
Intermittent prophylactic antibiotics for bronchiectasis (2022) · Cochrane
no estimate extractedNRNo studies
ISBCS vs DSBCS
Total costs per QALY · people with bilateral age‐related cataracts (NRSs)
Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts (2022) · Cochrane
no estimate extractedNRNo studies
ISBCS vs DSBCS
BCDVA · people with bilateral age‐related cataracts (NRSs)
Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts (2022) · Cochrane
no estimate extractedNRNo studies
ISBCS vs DSBCS
PROM · people with bilateral age‐related cataracts (NRSs)
Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts (2022) · Cochrane
no estimate extractedNRNo studies
ISBCS vs DSBCS
Total costs per QALY · people with bilateral age‐related cataracts (RCTs)
Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts (2022) · Cochrane
no estimate extractedNRNo studies
Exercise plus PD&P vs PD&P only
Quality of Life: change in CFQ‐R score · children and young adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise plus PD&P vs PD&P only
Participant preference · children and young adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise plus PD&P vs PD&P only
Need for extra antibiotics (days) · children and young adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs underwater PEP (uPEP; also known
Pulmonary function: absolute change FEV1 % predicted · children and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs underwater PEP (uPEP; also known
Change in VO2 peak during maximal exercise · children and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs underwater PEP (uPEP; also known
Quality of life: change in CFQ‐R score · children and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs ACBT
Change in VO2 peak during maximal exercise · adolescents and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs underwater PEP (uPEP; also known
Adherence · children and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs underwater PEP (uPEP; also known
Need for extra antibiotics (days) · children and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Exercise vs ACBT
Quality of life · adolescents and adults with cystic fibrosis
Exercise versus airway clearance techniques for people with cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies