Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

346 questions in 59 reviews · Vascular

current versions
No studies 346 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Pseudoaneurysm · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
Exercise vs no exercise
Number of days on a ventilator · adults with clinically diagnosed AAA deemed suitable for elective repair
Prehabilitation exercise therapy before elective abdominal aortic aneurysm repair (2021) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Time to ulcer healing · participants with arterial ulcersa
Dressings and topical agents for arterial leg ulcers (2020) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Patient satisfaction and quality of life data · participants with arterial ulcersa
Dressings and topical agents for arterial leg ulcers (2020) · Cochrane
no estimate extractedNRNo studies
Atherectomy vs balloon angioplasty with primary stenting
Primary patency ( · people with PAD
Atherectomy for peripheral arterial disease (2020) · Cochrane
no estimate extractedNRNo studies
Atherectomy vs balloon angioplasty with primary stenting
Primary patency ( · people with PAD
Atherectomy for peripheral arterial disease (2020) · Cochrane
no estimate extractedNRNo studies
Angioplasty vs primary stenting
Improvement in walking distance as reported by the patient · patients with symptomatic Iliac artery lesions
Angioplasty versus stenting for iliac artery lesions (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs with active control (1)
Major bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs with active control (1)
Symptomatic DVT · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs with active control (1)
1‐year overall mortality · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs with active control (1)
Clinically relevant bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs active control (2)
Any VTE · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs active control (2)
1‐year overall mortality · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs active control (2)
Clinically relevant bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs active control (3)
Major bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs active control (3)
Any VTE · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs active control (3)
1‐year overall mortality · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Low‐molecular‐weight heparin vs active control (3)
Clinically relevant bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs no thromboprophylaxis
Symptomatic VTE · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs no thromboprophylaxis
Major bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs no thromboprophylaxis
Symptomatic PE · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs no thromboprophylaxis
Symptomatic DVT · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs no thromboprophylaxis
Any VTE · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin K antagonists vs placebo or no thromboprophylaxis
Any VTE · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin K antagonists vs placebo or no thromboprophylaxis
1‐year overall mortality · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin K antagonists vs placebo or no thromboprophylaxis
Clinically relevant bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin K antagonists vs active control
Any VTE · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin K antagonists vs active control
1‐year overall mortality · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Vitamin K antagonists vs active control
Clinically relevant bleeding · ambulatory cancer patients receiving chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Antithrombin vs no thromboprophylaxis
Symptomatic VTE · ambulatory paediatric cancer patients newly diagnosed with acute lymphoblastic leukaemia who received chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Antithrombin vs no thromboprophylaxis
Symptomatic PE · ambulatory paediatric cancer patients newly diagnosed with acute lymphoblastic leukaemia who received chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Antithrombin vs no thromboprophylaxis
Symptomatic DVT · ambulatory paediatric cancer patients newly diagnosed with acute lymphoblastic leukaemia who received chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Antithrombin vs no thromboprophylaxis
1‐year overall mortality · ambulatory paediatric cancer patients newly diagnosed with acute lymphoblastic leukaemia who received chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Antithrombin vs no thromboprophylaxis
Clinically relevant bleeding · ambulatory paediatric cancer patients newly diagnosed with acute lymphoblastic leukaemia who received chemotherapy
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy (2020) · Cochrane
no estimate extractedNRNo studies
Alternative modes of exercise vs walking exercise
Health‐related QoL (at end of training, ranging from 12 to 24 weeks) · patients with IC
Modes of exercise training for intermittent claudication (2020) · Cochrane
no estimate extractedNRNo studies
Low molecular weight heparin (LMWH) vs no LMWH
Complication and adverse reactions ‐ wound bleeding (analysed by participant, · patients undergoing digital replantation after traumatic amputation
Low molecular weight heparin for prevention of microvascular occlusion in digital replantation (2020) · Cochrane
no estimate extractedNRNo studies
Low molecular weight heparin vs unfractionated heparin
Incidence of compromised microcirculation requiring invasive intervention (re‐exploration) (analysed by participant/digit, · patients undergoing digital replantation after traumatic amputation
Low molecular weight heparin for prevention of microvascular occlusion in digital replantation (2020) · Cochrane
no estimate extractedNRNo studies
Low molecular weight heparin vs unfractionated heparin
Incidence of compromised microcirculation requiring invasive intervention (incision) (analysed by participant/digit, · patients undergoing digital replantation after traumatic amputation
Low molecular weight heparin for prevention of microvascular occlusion in digital replantation (2020) · Cochrane
no estimate extractedNRNo studies
Low molecular weight heparin (LMWH) vs no LMWH
Success rate of replantation1 (analysed by participant) · patients undergoing digital replantation after traumatic amputation
Low molecular weight heparin for prevention of microvascular occlusion in digital replantation (2020) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Additional side effects of heparin · children with congenital heart disease undergoing CC
Different unfractionated heparin doses for preventing arterial thrombosis in children undergoing cardiac… (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs low molecular weight heparin
Total VTE (fatal and non‐fatal) · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Heparin vs placebo
Adverse events (timing not specified) · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs low molecular weight heparin
PE (symptomatic, asymptomatic, non‐fatal) · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs low molecular weight heparin
All cause mortality · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs low molecular weight heparin
Adverse events · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Unfractionated heparin vs low molecular weight heparin
Bleeding (timing not specified) · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Heparin vs placebo
Total VTE (fatal and non‐fatal) · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Heparin vs placebo
DVT (symptomatic, asymptomatic, non‐fatal) · people undergoing major amputation of the lower extremity
Primary prophylaxis for venous thromboembolism in people undergoing major amputation of the lower extremity (2020) · Cochrane
no estimate extractedNRNo studies
Any pharmacological agent vs placebo or any other pharmacological agent
Ulcer healing · patients with Buerger's disease
Pharmacological treatment for Buerger's disease (2020) · Cochrane
no estimate extractedNRNo studies
Intravenous prostacyclin analogue vs intravenous prostaglandin analogue
Rate of amputation · patients with Buerger's disease
Pharmacological treatment for Buerger's disease (2020) · Cochrane
no estimate extractedNRNo studies