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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

302 questions in 48 reviews · Neuromuscular

current versions
No studies 302 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Electroacupuncture vs night splints
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs placebo/sham acupuncture
Overall clinical improvement (at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus NSAID plus vitamins vs NSAID plus vitamins
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus NSAID plus vitamins vs NSAID plus vitamins
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Laser acupuncture vs placebo/sham laser acupuncture
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Absorbable vs non‐absorbable sutures
Adverse outcomes including wound infection, scar breakdown or return to theatre
Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery (2018) · Cochrane
no estimate extractedNRNo studies
Absorbable vs non‐absorbable sutures
Postoperative scar satisfaction
Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery (2018) · Cochrane
no estimate extractedNRNo studies
Absorbable vs non‐absorbable sutures
Adverse outcomes including wound infection, scar breakdown or return to theatre
Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery (2018) · Cochrane
no estimate extractedNRNo studies
Absorbable vs non‐absorbable sutures
Postoperative pain: late pain (6 weeks postoperatively)
Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery (2018) · Cochrane
no estimate extractedNRNo studies
Absorbable vs non‐absorbable sutures
Postoperative hand function
Absorbable versus non‐absorbable sutures for skin closure after carpal tunnel decompression surgery (2018) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Change in disability after one year · people with chronic inflammatory demyelinating polyradiculoneuropathy
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy (2017) · Cochrane
no estimate extractedNRNo studies
Monthly pulsed high‐dose dexamethasone vs oral prednisolone
Change in disability after one year · people with chronic inflammatory demyelinating polyradiculoneuropathy
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy (2017) · Cochrane
no estimate extractedNRNo studies
Interferon beta‐1a vs placebo
Change in disability after 26 or more weeks · people with CIDP
Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic… (2017) · Cochrane
no estimate extractedNRNo studies
Non‐invasive ventilation vs standard care
Quality of life (SF‐36 PCS) · people with ALS
Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease (2017) · Cochrane
no estimate extractedNRNo studies
Non‐invasive ventilation vs standard care
Adverse events (not reported) · people with ALS
Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy vs ultrasound
Adverse events · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy vs fascial manipulation
Overall improvement in CTS:SSS: long term ‐ not reported · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy vs fascial manipulation
Overall improvement in CTS: FSS: long term · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy vs fascial manipulation
Adverse events · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy and a splint vs ultrasound and a splint
Overall improvement in CTS:SSS: long term ‐ not measured · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy and a splint vs ultrasound and a splint
Overall improvement in CTS: FSS: long term ‐ not reported · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy and a splint vs ultrasound and a splint
Adverse events · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy and a splint vs placebo and a splint
Overall improvement in CTS: SSS: long term ‐ not measured · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy and a splint vs placebo and a splint
Overall improvement in CTS: FSS: long term ‐ not measured · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy, wrist splint, and vitamin B6 vs placebo, wrist splint, and vitamin B6
Overall improvement in CTS: SSS: long term ‐ not measured · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy, wrist splint, and vitamin B6 vs placebo, wrist splint, and vitamin B6
Overall improvement in CTS: FSS: long term ‐ not reported · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy, wrist splint, and vitamin B6 vs placebo, wrist splint, and vitamin B6
Adverse events · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Low‐level laser therapy vs placebo
Adverse events · carpal tunnel syndrome
Low‐level laser therapy for carpal tunnel syndrome (2017) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Prolongation of time to loss of ambulation ‐ not reported · patients with Duchenne muscular dystrophy
Corticosteroids for the treatment of Duchenne muscular dystrophy (2016) · Cochrane
no estimate extractedNRNo studies
Deflazacort vs prednisone
Prolongation of time to loss of ambulation ‐ not reported · patients with Duchenne muscular dystrophy
Corticosteroids for the treatment of Duchenne muscular dystrophy (2016) · Cochrane
no estimate extractedNRNo studies
Deflazacort vs prednisone
Muscle strength ‐ not reported · patients with Duchenne muscular dystrophy
Corticosteroids for the treatment of Duchenne muscular dystrophy (2016) · Cochrane
no estimate extractedNRNo studies
Deflazacort vs prednisone
Change in 10‐metre walking time · patients with Duchenne muscular dystrophy
Corticosteroids for the treatment of Duchenne muscular dystrophy (2016) · Cochrane
no estimate extractedNRNo studies
Deflazacort vs prednisone
Change in 4‐stair climbing time · patients with Duchenne muscular dystrophy
Corticosteroids for the treatment of Duchenne muscular dystrophy (2016) · Cochrane
no estimate extractedNRNo studies
Deflazacort vs prednisone
Fractures · patients with Duchenne muscular dystrophy
Corticosteroids for the treatment of Duchenne muscular dystrophy (2016) · Cochrane
no estimate extractedNRNo studies
Weekend‐only vs daily prednisone
Prolongation of time to loss of ambulation ‐ not reported · patients with Duchenne muscular dystrophy
Corticosteroids for the treatment of Duchenne muscular dystrophy (2016) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Change in nerve pain and in nerve tenderness at 1 year ‐ not reported · people with nerve damage (6 to 24 months' duration) in leprosy
Corticosteroids for treating nerve damage in leprosy (2016) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Limitations in activities of daily living at 1 year ‐ not reported · people with nerve damage (6 to 24 months' duration) in leprosy
Corticosteroids for treating nerve damage in leprosy (2016) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Limitations in participation at 1 year ‐ not reported · people with nerve damage (6 to 24 months' duration) in leprosy
Corticosteroids for treating nerve damage in leprosy (2016) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Improvement in motor nerve function at 1 year ‐ not reported · people with nerve damage (< 6 months' duration) in leprosy
Corticosteroids for treating nerve damage in leprosy (2016) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Change in nerve pain and in nerve tenderness at 1 year ‐ not reported · people with nerve damage (< 6 months' duration) in leprosy
Corticosteroids for treating nerve damage in leprosy (2016) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Limitations in activities of daily living at 1 year ‐ not reported · people with nerve damage (< 6 months' duration) in leprosy
Corticosteroids for treating nerve damage in leprosy (2016) · Cochrane
no estimate extractedNRNo studies
Corticosteroids vs placebo
Limitations in participation at 1 year ‐ not reported · people with nerve damage (< 6 months' duration) in leprosy
Corticosteroids for treating nerve damage in leprosy (2016) · Cochrane
no estimate extractedNRNo studies
Antioxidant vs placebo
Survival (not measured) · people with Friedreich ataxia
Pharmacological treatments for Friedreich ataxia (2016) · Cochrane
no estimate extractedNRNo studies
Interferon beta‐1a vs placebo
Change in timed walk at 6 months (%) e.g. 10‐metre or 6‐minute walk test at 6 months ‐ not measured · people with inclusion body myositis
Treatment for inclusion body myositis (2015) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Change in muscle mass at 6 months (%) ‐ not measured · people with inclusion body myositis
Treatment for inclusion body myositis (2015) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Change in handgrip strength at 6 months (%) ‐ not measured · people with inclusion body myositis
Treatment for inclusion body myositis (2015) · Cochrane
no estimate extractedNRNo studies
Methotrexate vs placebo
Change in timed walk at 6 months (%) e.g. 10‐metre or 6‐minute walk test at 6 months ‐ not measured · people with inclusion body myositis
Treatment for inclusion body myositis (2015) · Cochrane
no estimate extractedNRNo studies
Intravenous immunoglobulin vs placebo
Change in muscle strength at 12 months (%) ‐ not measured · people with inclusion body myositis
Treatment for inclusion body myositis (2015) · Cochrane
no estimate extractedNRNo studies
Methotrexate and anti‐T lymphocyte immunoglobulin vs methotrexate
Change in muscle mass at 12 months (%) ‐ not measured · people with inclusion body myositis
Treatment for inclusion body myositis (2015) · Cochrane
no estimate extractedNRNo studies
Methotrexate and anti‐T lymphocyte immunoglobulin vs methotrexate
Change in timed walk at 6 months (%) e.g. 10‐metre or 6‐minute walk test at 6 months ‐ not measured · people with inclusion body myositis
Treatment for inclusion body myositis (2015) · Cochrane
no estimate extractedNRNo studies