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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings: inhaled TOBI® (IV preparation) vs tobramycin
Antibiotic resistance · adults and children with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: inhaled TOBI® (IV preparation) vs tobramycin
Adverse events · adults and children with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: tobramycin for inhalation powder vs tobramycin
FVC · children and adults with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: tobramycin for inhalation powder vs tobramycin
Quality of life · children and adults with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: aztreonam lysine for inhalation vs tobramycin
FVC · children and adults with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: amikacin liposome inhalation suspension (ALIS) vs tobramycin
FVC · children and adults with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: amikacin liposome inhalation suspension (ALIS) vs tobramycin
Survival · children and adults with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: levofloxacin for inhalation solution vs tobramycin
Survival · adults and children aged over 12 with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: continuous cycles alternating aztreonam lysine for inhalation with tobramycin for inhalation solution vs continuous cycles alternating placebo with tobramycin
FVC · children and adults with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings: continuous cycles alternating aztreonam lysine for inhalation with tobramycin for inhalation solution vs continuous cycles alternating placebo with tobramycin
Survival · children and adults with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Support plus vs usual care
Stopping breastfeeding (any) at 9 months ‐ not reported · healthy breastfeeding women with healthy term babies
Support for healthy breastfeeding mothers with healthy term babies (2022) · Cochrane
no estimate extractedNRNo studies
Intravenous ± oral steroids vs oral steroids alone
Complete or partial remission · minimal change disease in adults with nephrotic syndrome
Interventions for minimal change disease in adults with nephrotic syndrome (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mobility outcome · adults following hip fracture surgery
Interventions for improving mobility after hip fracture surgery in adults (2022) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mobility outcome · adults following hip fracture surgery
Interventions for improving mobility after hip fracture surgery in adults (2022) · Cochrane
no estimate extractedNRNo studies
Blastocyst‐stage vs cleavage‐stage embryo transfer
Outcomes per couple · women and couples with subfertility
Cleavage‐stage versus blastocyst‐stage embryo transfer in assisted reproductive technology (2022) · Cochrane
no estimate extractedNRNo studies
Virus vaccines vs placebo
Mortality: vaccine related and all cause ‐ not reported · young, healthy men in a military facility
Vaccines for the common cold (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings ‐ Hydroxyurea and phlebotomy vs transfusion and chelation
Quality of life · adults and children with sickle cell disease and an increased risk of stroke
Hydroxyurea (hydroxycarbamide) for sickle cell disease (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings ‐ Hydroxyurea vs observation
Pain alteration · adults and children with sickle cell disease and an increased risk of stroke
Hydroxyurea (hydroxycarbamide) for sickle cell disease (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings ‐ Hydroxyurea vs observation
Quality of life · adults and children with sickle cell disease and an increased risk of stroke
Hydroxyurea (hydroxycarbamide) for sickle cell disease (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings ‐ Hydroxyurea vs no hydroxyurea
Pain alteration · adults and children with sickle cell disease
Hydroxyurea (hydroxycarbamide) for sickle cell disease (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings ‐ Hydroxyurea vs no hydroxyurea
Life‐threatening illness · adults and children with sickle cell disease
Hydroxyurea (hydroxycarbamide) for sickle cell disease (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings ‐ Hydroxyurea vs no hydroxyurea
Quality of life · adults and children with sickle cell disease
Hydroxyurea (hydroxycarbamide) for sickle cell disease (2022) · Cochrane
no estimate extractedNRNo studies
Comparison 1: Alpha‐blockers vs placebo
Treatment efficacy ‐ treatment response, as measured by the Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults (aged 18‐85)
Pharmacotherapy for post traumatic stress disorder (PTSD) (2022) · Cochrane
no estimate extractedNRNo studies
Comparison 3: MAOIs vs placebo
Treatment efficacy ‐ treatment response, as measured by the Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults (aged 18‐85)
Pharmacotherapy for post traumatic stress disorder (PTSD) (2022) · Cochrane
no estimate extractedNRNo studies
Comparison 5: SNRIs vs placebo
Treatment efficacy ‐ treatment response, as measured by the Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults (aged 18‐85)
Pharmacotherapy for post traumatic stress disorder (PTSD) (2022) · Cochrane
no estimate extractedNRNo studies
Medical abortion administered by nurses vs by doctors
Nausea · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Oral misoprostol vs vaginal misoprostol
Women's dissatisfaction with the procedure · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Oral misoprostol vs vaginal misoprostol
Blood transfusion · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Sublingual misoprostol vs vaginal misoprostol
Blood transfusion · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Mifepristone alone vs mifepristone/prostaglandin
Nausea · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Mifepristone alone vs mifepristone/prostaglandin
Women's dissatisfaction with the procedure · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Mifepristone alone vs mifepristone/prostaglandin
Blood transfusion · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Mifepristone (600 mg) plus prostaglandin vs mifepristone (200 mg) plus prostaglandin
Women's dissatisfaction with the procedure · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Oral misoprostol alone vs vaginal misoprostol alone
Blood transfusion · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Mifepristone (600 mg) plus prostaglandin vs mifepristone (200 mg) plus prostaglandin
Blood transfusion · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Misoprostol 800 µg plus mifepristone 200 mg vs misoprostol 400 µg plus mifepristone 200 mg
Blood transfusion · women undergoing first trimester abortion
Medical methods for first trimester abortion (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Pseudophakia vs aphakia
Amblyopia ‐ not reported · children younger than two years of age with bilateral congenital cataracts
Surgical interventions for bilateral congenital cataract in children aged two years and under (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Pseudophakia vs aphakia
Retinal detachment ‐ not reported · children younger than two years of age with bilateral congenital cataracts
Surgical interventions for bilateral congenital cataract in children aged two years and under (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Pseudophakia vs aphakia
Reoperation rate ‐ not reported · children younger than two years of age with bilateral congenital cataracts
Surgical interventions for bilateral congenital cataract in children aged two years and under (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Prone vs supine
Mortality (respiratory events) ‐ not reported · acute respiratory distress in hospitalised infants and children (ARDs)
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung dependent
Blood gases (PaCO2) ‐ not reported · acute respiratory distress in hospitalised infants and children (ARDs)
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung dependent
Lung function (PaO2/FiO2 ratio) ‐ not reported · acute respiratory distress in hospitalised infants and children (ARDs)
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung dependent
Oxygenation index (FiO2% X MPAW/PaO2) ‐ not reported · acute respiratory distress in hospitalised infants and children (ARDs)
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung dependent
Potential adverse outcomes (episodes of apnoea) ‐ not reported · acute respiratory distress in hospitalised infants and children (ARDs)
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung independent
Mortality (respiratory events) ‐ not reported · acute respiratory distress in hospitalised infants and children
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung independent
Oxygen saturation (SaO2) ‐ not reported · acute respiratory distress in hospitalised infants and children
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung independent
Blood gases (PCO2) ‐ not reported · acute respiratory distress in hospitalised infants and children
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung independent
Lung function (PaO2/FiO2 ratio) ‐ not reported · acute respiratory distress in hospitalised infants and children
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung independent
Oxygenation index (FiO2% X MPAW/PaO2) ‐ not reported · acute respiratory distress in hospitalised infants and children
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Supine vs good‐lung independent
Potential adverse outcomes (episodes of apnoea) ‐ not reported · acute respiratory distress in hospitalised infants and children
Positioning for acute respiratory distress in hospitalised infants and children (2022) · Cochrane
no estimate extractedNRNo studies