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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
361 questions in 74 reviews · Pain, Palliative and Supportive Care
current versionsNo studies 361 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Summary of findings: haloperidol vs placebo Agitation within 24 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: haloperidol vs lorazepam Symptoms of delirium within 24 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: haloperidol vs lorazepam Agitation within 24 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: haloperidol vs lorazepam Agitation between 24 and 48 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: lorazepam vs chlorpromazine Symptoms of delirium within 24 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: lorazepam vs chlorpromazine Agitation within 24 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: lorazepam vs chlorpromazine Agitation between 24 and 48 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: haloperidol vs risperidone Agitation within 24 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Summary of findings: haloperidol vs risperidone Agitation between 24 and 48 hours · terminally ill adults with delirium Drug therapy for delirium in terminally ill adults (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline,… Interventions for the management of malignant pleural effusions: a network meta‐analysis (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Doxycycline · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline,… Interventions for the management of malignant pleural effusions: a network meta‐analysis (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline,… Interventions for the management of malignant pleural effusions: a network meta‐analysis (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline,… Interventions for the management of malignant pleural effusions: a network meta‐analysis (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Doxycycline · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline,… Interventions for the management of malignant pleural effusions: a network meta‐analysis (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline,… Interventions for the management of malignant pleural effusions: a network meta‐analysis (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs other VR distraction Acute pain intensity: self‐report (during procedure) · children (0‐18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs other VR distraction Acute pain intensity: observer‐report (during procedure) · children (0‐18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs other VR distraction Acute pain intensity: behavioural measurement (observer‐report) (during procedure) · children (0‐18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs other VR distraction Acute pain intensity: self‐report (post‐procedure) · children (0‐18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs other VR distraction Acute pain intensity: observer‐report (post‐procedure) · children (0‐18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs no distraction Acute pain intensity: observer‐report (during procedure) · children (0 to 18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs other VR distraction Acute pain intensity: behavioural measurement (observer‐report) (post‐procedure) · children (0‐18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Virtual reality distraction vs other VR distraction Adverse effects (related to engagement with VR) · children (0‐18 years) Virtual reality distraction for acute pain in children (2020) · Cochrane | no estimate extracted | NR | No studies |
Herbal treatment vs placebo Participant‐reported pain relief of 50% or greater Immediately post‐intervention · adults with neuropathic pain Herbal medicinal products or preparations for neuropathic pain (2019) · Cochrane | no estimate extracted | NR | No studies |
Herbal treatment vs placebo Participant‐reported global impression of clinical change (PGIC) much or very much improved (moderate) Immediately post‐intervention · adults with neuropathic pain Herbal medicinal products or preparations for neuropathic pain (2019) · Cochrane | no estimate extracted | NR | No studies |
Herbal treatment vs placebo Participant‐reported global impression of clinical change (PGIC) very much improved (substantial) Immediately post‐intervention · adults with neuropathic pain Herbal medicinal products or preparations for neuropathic pain (2019) · Cochrane | no estimate extracted | NR | No studies |
Non‐steroidal anti‐inflammatory drugs (NSAID) vs placebo Participant‐reported pain relief of 50% or greater · adults with sickle cell disease in a vaso‐occlusive crises Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs placebo PGIC very much improved · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs placebo PGIC much or very much improved · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs placebo Any adverse event · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs placebo Serious adverse event · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs placebo Withdrawals due to adverse events · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs active comparator Participant‐reported pain relief of 50% or greater · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs active comparator Participant‐reported pain relief of 30% or greater · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs active comparator PGIC much or very much improved · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Non‐steroidal anti‐inflammatory drugs (NSAID) vs placebo Participant‐reported pain relief of 30% or greater · adults with sickle cell disease in a vaso‐occlusive crises Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs active comparator Withdrawals due to adverse events · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs placebo Participant‐reported pain relief of 50% or greater · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Opioids vs placebo Participant‐reported pain relief of 30% or greater · adults with sickle cell disease in a vaso‐occlusive crisis Pharmacological interventions for painful sickle cell vaso‐occlusive crises in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Systemic corticosteroids vs placebo Patient satisfaction with treatment · adults with cancer‐related breathlessness (dyspnoea) Systemic corticosteroids for the management of cancer‐related breathlessness (dyspnoea) in adults (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR CI: Confidence interval. · Children and adolescents with chronic pain Psychological therapies for the management of chronic and recurrent pain in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Hypnosis vs control Observer‐reported pain · children aged 3‐16 years with chronic illness (cancer) or generally healthy undergoing bone marrow aspirations, lumbar… Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Preparation/information vs control Self‐reported distress · children aged 3‐12 years with mixed medical (acute or chronic illness) or unclear diagnoses undergoing venipuncture or… Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Breathing vs control Self‐reported distress · children aged 6‐15 years who are generally healthy, undergoing surgery, or have leukemia undergoing venipuncture or… Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Breathing vs control Behavioral measures‐ pain · children aged 6‐15 years who are generally healthy, undergoing surgery, or have leukemia undergoing venipuncture or… Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Breathing vs control Behavioral measures‐ distress · children aged 6‐15 years who are generally healthy, undergoing surgery, or have leukemia undergoing venipuncture or… Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Suggestion vs control Behavioral measures‐ pain · children aged 3‐17 years who are generally healthy or have chronic illness undergoing intramuscular injection,… Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Suggestion vs control Behavioral measures‐ distress · children aged 3‐17 years who are generally healthy or have chronic illness undergoing intramuscular injection,… Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Memory alteration vs control Self‐reported distress · children aged 3‐18 years with chronic illness (leukemia) undergoing lumbar puncture Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |
Memory alteration vs control Behavioral measures‐ pain · children aged 3‐18 years with chronic illness (leukemia) undergoing lumbar puncture Psychological interventions for needle‐related procedural pain and distress in children and adolescents (2018) · Cochrane | no estimate extracted | NR | No studies |