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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

542 questions in 42 reviews · Skin

current versions
No studies 542 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Cefadroxil vs flucloxacillin
Recurrence of folliculitis or boil following completion of treatment · bacterial furunculosis
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs topical antiseptics
Severe adverse events leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Cefdinir vs cefalexin
Quality of life · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Cefdinir vs cefalexin
Recurrence of folliculitis or boil following completion of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Azithromycin vs cefaclor
Quality of life · bacterial boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Azithromycin vs cefaclor
Recurrence of folliculitis or boil following completion of treatment · bacterial boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs topical antiseptics
Quality of life · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Cefditoren pivoxil vs cefaclor
Quality of life · bacterial boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Cefditoren pivoxil vs cefaclor
Recurrence of folliculitis or boil following completion of treatment · bacterial boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs topical antiseptics
Recurrence of folliculitis or boil following completion of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs topical antiseptics
Minor adverse events not leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs systemic antibiotics
Clinical cure · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs systemic antibiotics
Severe adverse events leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs systemic antibiotics
Quality of life · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Topical antibiotics vs systemic antibiotics
Recurrence of folliculitis or boil following completion of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ NB‐UVB vs PUVA
Patient‐reported changes in symptoms ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ NB‐UVB vs PUVA
Health‐related quality of life ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ UVA1 vs PUVA
Patient‐reported changes in symptoms ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ UVA1 vs PUVA
Investigator Global Assessment ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ UVA1 vs PUVA
Health‐related quality of life ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ UVA1 vs PUVA
Safety: withdrawals due to adverse events ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ NB‐UVB vs placebo
Health‐related quality of life ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ NB‐UVB vs UVA1
Investigator Global Assessment ‐ not measured · atopic eczema
Phototherapy for atopic eczema (2021) · Cochrane
no estimate extractedNRNo studies
Imiquimod vs surgical excision
Early treatment failure · adults with basal cell carcinoma of the skin
Interventions for basal cell carcinoma of the skin (2020) · Cochrane
no estimate extractedNRNo studies
Radiotherapy vs surgical excision (with or without frozen section margin control)
Pain · adults with basal cell carcinoma of the skin
Interventions for basal cell carcinoma of the skin (2020) · Cochrane
no estimate extractedNRNo studies
Radiotherapy vs surgical excision (with or without frozen section margin control)
Early treatment failure · adults with basal cell carcinoma of the skin
Interventions for basal cell carcinoma of the skin (2020) · Cochrane
no estimate extractedNRNo studies
Mohs micrographic surgery vs surgical excision
Pain · adults with basal cell carcinoma of the skin
Interventions for basal cell carcinoma of the skin (2020) · Cochrane
no estimate extractedNRNo studies
Mohs micrographic surgery vs surgical excision
Early treatment failure · adults with basal cell carcinoma of the skin
Interventions for basal cell carcinoma of the skin (2020) · Cochrane
no estimate extractedNRNo studies
Azithromycin (500 mg 20 ‐ 28 days) vs meglumine antimoniate (15 ‐ 20 mg/kg/d
Recurrence ‐ not measured · People with American cutaneous and mucocutaneous leishmaniasis
Interventions for American cutaneous and mucocutaneous leishmaniasis (2020) · Cochrane
no estimate extractedNRNo studies
Topical imiquimod 5% (3 times/week) + meglumine antimoniate (IVMA) (20 mg/kg/d for 20 days) vs placebo + IVMA
Recurrence ‐ not measured · People with American cutaneous leishmaniasis
Interventions for American cutaneous and mucocutaneous leishmaniasis (2020) · Cochrane
no estimate extractedNRNo studies
Thermotherapy one session (at 50 ºC for 30 seconds) vs meglumine antimoniate (20 mg Sb5/kg/day
Recurrence ‐ not measured · People with American cutaneous leishmaniasis
Interventions for American cutaneous and mucocutaneous leishmaniasis (2020) · Cochrane
no estimate extractedNRNo studies
Pentoxifylline (oral 400 mg thrice daily) plus meglumine antimoniate (IMMA) (20 mg/ kg /day for 20 days) vs IMMA plus placebo
Recurrence ‐ not measured · People with American cutaneous leishmaniasis
Interventions for American cutaneous and mucocutaneous leishmaniasis (2020) · Cochrane
no estimate extractedNRNo studies
Oral miltefosine (1.2 to 3.3 mg/kg/d 28 days) vs meglumine antimoniate (20 mg/kg 20 days)
Recurrence ‐ not measured · People with American cutaneous and mucocutaneous leishmaniasis
Interventions for American cutaneous and mucocutaneous leishmaniasis (2020) · Cochrane
no estimate extractedNRNo studies
IFN‐α + PUVA vs PUVA alone
Improvement of quality of life · people with mycosis fungoides
Interventions for mycosis fungoides (2020) · Cochrane
no estimate extractedNRNo studies
IFN‐α + acitretin vs IFN‐α + PUVA
Improvement of quality of life · people with mycosis fungoides
Interventions for mycosis fungoides (2020) · Cochrane
no estimate extractedNRNo studies
IFN‐α + acitretin vs IFN‐α + PUVA
Objective response rate · people with mycosis fungoides
Interventions for mycosis fungoides (2020) · Cochrane
no estimate extractedNRNo studies
IFN‐α + PUVA vs PUVA alone
Common adverse effects · people with mycosis fungoides
Interventions for mycosis fungoides (2020) · Cochrane
no estimate extractedNRNo studies
IFN‐α + PUVA vs PUVA alone
Objective response rate (ORR) · people with mycosis fungoides
Interventions for mycosis fungoides (2020) · Cochrane
no estimate extractedNRNo studies
Extracorporeal photopheresis vs PUVA
Improvement of quality of life · people with mycosis fungoides
Interventions for mycosis fungoides (2020) · Cochrane
no estimate extractedNRNo studies
Bexarotene + PUVA vs PUVA alone
Improvement of quality of life · people with mycosis fungoides
Interventions for mycosis fungoides (2020) · Cochrane
no estimate extractedNRNo studies
Benzoyl peroxide vs erythromycin
Participant's global self‐assessment of improvement (long‐term data) ‐ not measured · acne vulgaris
Topical benzoyl peroxide for acne (2020) · Cochrane
no estimate extractedNRNo studies
Benzoyl peroxide vs salicylic acid
Participant's global self‐assessment of improvement (long‐term data) ‐ not measured · acne vulgaris
Topical benzoyl peroxide for acne (2020) · Cochrane
no estimate extractedNRNo studies
Azelaic acid vs clindamycin
Quality of life · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies
Azelaic acid vs tretinoin
Total number of participants who experienced at least one minor adverse event · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies
Azelaic acid vs tretinoin
Quality of life · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies
Salicylic acid vs benzoyl peroxide
Participants' global self‐assessment of acne improvement · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies
Salicylic acid vs pyruvic acid
Total number of participants who experienced at least one minor adverse event · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies
Salicylic acid vs pyruvic acid
Quality of life · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies
Nicotinamide vs clindamycin
Participants' global self‐assessment of acne improvement · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies
Nicotinamide vs clindamycin
Quality of life · participants with acne
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane
no estimate extractedNRNo studies