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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

726 questions in 98 reviews · Pregnancy and Childbirth

current versions
No studies 726 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Probiotics vs placebo
Postnatal depression · preventing gestational diabetes
Probiotics for preventing gestational diabetes (2021) · Cochrane
no estimate extractedNRNo studies
Probiotics vs placebo
Development of subsequent diabetes · preventing gestational diabetes
Probiotics for preventing gestational diabetes (2021) · Cochrane
no estimate extractedNRNo studies
NSAID (single administration, any dose) vs paracetamol
Neonatal drug adverse effects ‐ not reported · women with perineal pain in the early postpartum period
Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period (2021) · Cochrane
no estimate extractedNRNo studies
NSAID vs placebo
Neonatal drug adverse effects · women with perineal pain in the early postpartum period
Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period (2021) · Cochrane
no estimate extractedNRNo studies
Non‐pharmacological interventions for fear of childbirth (tocophobia) vs usual care
Anxiety ‐ not reported · women with fear of childbirth (tocophobia)
Interventions for fear of childbirth including tocophobia (2021) · Cochrane
no estimate extractedNRNo studies
Oral misoprostol vs placebo/no treatment
Vaginal birth within 24 hours · women with ruptured membranes in the third trimester for induction of labour.
Low‐dose oral misoprostol for induction of labour (2021) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs vaginal/intracervical prostaglandins
Uterine hyperstimulation with/without fetal heart rate (FHR) changes ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs intravenous oxytocin/amniotomy
Spontaneous vaginal birth ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs intravenous oxytocin/amniotomy
Uterine hyperstimulation with/without fetal heart (FHR) rate changes ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs intravenous oxytocin/amniotomy
Neonatal death or serious neonatal perinatal morbidity · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs vaginal/oral misoprostol
Spontaneous onset of labour ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs vaginal/oral misoprostol
Induction of labour ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs vaginal/oral misoprostol
Spontaneous vaginal birth ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs vaginal/oral misoprostol
Uterine hyperstimulation with/without fetal heart rate (FHR) changes ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs vaginal/oral misoprostol
Maternal death or serious maternal morbidity · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs vaginal/oral misoprostol
Neonatal death or serious neonatal perinatal morbidity ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
One frequency of amniotic membranes sweeping vs another frequency of amniotic membrane sweeping
Spontaneous onset of labour ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
One frequency of amniotic membranes sweeping vs another frequency of amniotic membrane sweeping
Uterine hyperstimulation with/without fetal heart rate (FHR) changes ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Amniotic membranes sweeping vs no treatment/sham
Uterine hyperstimulation with/without fetal heart rate (FHR) changes ‐ not reported · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).
Membrane sweeping for induction of labour (2020) · Cochrane
no estimate extractedNRNo studies
Crystalloid vs control
Neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Crystalloid vs control
Admission to neonatal intensive care unit · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Colloid vs crystalloid
Admission to neonatal intensive care unit · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Ephedrine vs phenylephrine
Admission to neonatal intensive care unit · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Ondansetron vs control
Maternal hypertension requiring intervention · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Ondansetron vs control
Admission to neonatal care unit · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Lower limb compression vs control
Maternal hypertension requiring intervention · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Lower limb compression vs control
Neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Lower limb compression vs control
Admission to neonatal intensive care unit · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Walking vs lying
Maternal hypertension requiring intervention · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Walking vs lying
Maternal bradycardia requiring intervention · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Walking vs lying
Maternal nausea and/or vomiting · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Walking vs lying
Neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Walking vs lying
Neonal Apgar score < 8 at 5 minutes · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Walking vs lying
Admission to neonatal intensive care unit · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Crystalloid vs control
Maternal hypertension requiring intervention · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Crystalloid vs control
Maternal bradycardia requiring intervention · women having spinal anaesthesia for caesarean section
Techniques for preventing hypotension during spinal anaesthesia for caesarean section (2020) · Cochrane
no estimate extractedNRNo studies
Any antibiotics vs placebo or no treatment
Fever ‐ not measured · operative vaginal delivery
Antibiotic prophylaxis for operative vaginal delivery (2020) · Cochrane
no estimate extractedNRNo studies
Any antibiotics vs placebo or no treatment
Urinary tract infection ‐ not measured · operative vaginal delivery
Antibiotic prophylaxis for operative vaginal delivery (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs opioid
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs opioid
Duration of hospital stay · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs opioid
Any breastfeeding at hospital discharge · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
NSAID vs opioid
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Opioid vs placebo
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Opioid vs placebo
Duration of hospital stay · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Opioid vs placebo
Any breastfeeding at hospital discharge · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Opioid vs placebo
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Paracetamol vs placebo
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Paracetamol vs placebo
Duration of hospital stay · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Paracetamol vs placebo
Any breastfeeding at hospital discharge · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies
Paracetamol vs placebo
Any breastfeeding at 6 weeks postpartum · women who have given birth vaginally, requiring analgesia for after‐birth pains.
Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane
no estimate extractedNRNo studies