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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
587 questions in 116 reviews · Eyes and Vision
current versionsNo studies 587 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Rho kinase inhibitor vs beta‐blocker Glaucoma progression at 12 months, defined by anatomic (structural) criteriab · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs beta‐blocker Patient‐reported outcome at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs beta‐blocker Mean change in the number of glaucoma medications at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs beta‐blocker Need for additional treatment at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs prostaglandin analog Glaucoma progression at 12 months, measured by additional visual field defects · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs prostaglandin analog Glaucoma progression at 12 months, defined by anatomic (structural) criteriab · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs prostaglandin analog Patient‐reported outcome at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs prostaglandin analog Mean change in the number of glaucoma medications at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs prostaglandin analog Need for additional treatment at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs prostaglandin analoga Glaucoma progression at 12 months, measured by additional visual field defects · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs prostaglandin analoga Glaucoma progression at 12 months, defined by anatomic (structural) criteriab · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs prostaglandin analoga Patient‐reported outcome at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs prostaglandin analoga Mean change in the number of glaucoma medications at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs prostaglandin analoga Need for additional treatment at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs rho kinase inhibitor Glaucoma progression at 12 months, measured by additional visual field defects · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs placeboa Glaucoma progression at 12 months, defined by anatomic (structural) criteriad · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs rho kinase inhibitor Glaucoma progression at 12 months, defined by anatomic (structural) criteriab · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs rho kinase inhibitor Patient‐reported outcome at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs rho kinase inhibitor Mean change in the number of glaucoma medications at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and prostaglandin analog vs rho kinase inhibitor Need for additional treatment at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and beta‐blocker vs beta‐blocker Glaucoma progression at 12 months, measured by additional visual field defects · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and beta‐blocker vs beta‐blocker Glaucoma progression at 12 months, defined by anatomic (structural) criteriab · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and beta‐blocker vs beta‐blocker Patient‐reported outcome at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs placeboa Patient‐reported outcome at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and beta‐blocker vs beta‐blocker Mean change in the number of glaucoma medications at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor and beta‐blocker vs beta‐blocker Need for additional treatment at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs placeboa Mean change in the number of glaucoma medications at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs placeboa Need for additional treatment at the longest · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Rho kinase inhibitor vs beta‐blocker Glaucoma progression at 12 months, measured by additional visual field defects · people with primary open‐angle glaucoma or ocular hypertension Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension (2022) · Cochrane | no estimate extracted | NR | No studies |
Topical antibiotics vs another topical antibiotic or placebo Change in pain intensity from baseline to 1 month · children and adults with corneal abrasion Antibiotic prophylaxis for corneal abrasion (2022) · Cochrane | no estimate extracted | NR | No studies |
Topical antibiotics vs another topical antibiotic or placebo Recurrent corneal erosion within 1 year · children and adults with corneal abrasion Antibiotic prophylaxis for corneal abrasion (2022) · Cochrane | no estimate extracted | NR | No studies |
Topical antibiotics vs another topical antibiotic or placebo Change in visual acuity from baseline to 1 year, or loss of 1 or more lines of best‐corrected visual acuity at 1 month · children and adults with corneal abrasion Antibiotic prophylaxis for corneal abrasion (2022) · Cochrane | no estimate extracted | NR | No studies |
Topical antibiotics vs another topical antibiotic or placebo Quality of life at 1 month · children and adults with corneal abrasion Antibiotic prophylaxis for corneal abrasion (2022) · Cochrane | no estimate extracted | NR | No studies |
Steroids with or without azathioprine vs cyclosporine A Proportion of participants achieving a 2‐line improvement in visual acuity (Snellen chart) (higher scores indicate better vision) · NIIPPU Non‐biologic, steroid‐sparing therapies for non‐infectious intermediate, posterior, and panuveitis in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Steroids with or without azathioprine vs cyclosporine A Proportion of participants with confirmed macular edema (lower number of events is better) · NIIPPU Non‐biologic, steroid‐sparing therapies for non‐infectious intermediate, posterior, and panuveitis in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Non‐biologic disease‐modifying antirheumatic drugs (DMARDs) vs steroid Proportion of participants achieving a 2‐line improvement in visual acuity (Snellen chart) (higher scores indicate better vision) Â · NIIPPU Non‐biologic, steroid‐sparing therapies for non‐infectious intermediate, posterior, and panuveitis in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Non‐biologic disease‐modifying antirheumatic drugs (DMARDs) vs steroid Proportion of participants with confirmed macular edema (lower number of events is better) · NIIPPU Non‐biologic, steroid‐sparing therapies for non‐infectious intermediate, posterior, and panuveitis in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Non‐biologic disease‐modifying antirheumatic drugs (DMARDs) vs steroid Proportion of participants achieving steroid‐sparing control (higher number of events is better) · NIIPPU Non‐biologic, steroid‐sparing therapies for non‐infectious intermediate, posterior, and panuveitis in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Methotrexate vs mycophenolate Proportion of participants achieving a 2‐line improvement in visual acuity (Snellen chart) (higher scores indicate better vision) · NIIPPU Non‐biologic, steroid‐sparing therapies for non‐infectious intermediate, posterior, and panuveitis in adults (2022) · Cochrane | no estimate extracted | NR | No studies |
Steroids vs cyclosporine A Adverse effect: new cataract formation · people with dry eye Topical corticosteroids for dry eye (2022) · Cochrane | no estimate extracted | NR | No studies |
Steroids vs lubricants Change in patient‐reported quality of life scores · people with dry eye Topical corticosteroids for dry eye (2022) · Cochrane | no estimate extracted | NR | No studies |
Steroids vs cyclosporine A Change in patient‐reported quality of life scores · people with dry eye Topical corticosteroids for dry eye (2022) · Cochrane | no estimate extracted | NR | No studies |
Patching vs active observation Stereoacuity at distance Loss of ≥ 2 octaves near stereoacuity, measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged less than 11 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |
Patching vs active observation Motor fusion test · people with intermittent exotropia, aged less than 11 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |
Patching vs active observation Minor adverse events Defined as any adverse event within 8 weeks of surgery that does not require further intervention · people with intermittent exotropia, aged less than 11 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |
Patching vs active observation Quality of life measures Measured at 3 years using the IXTQ scores for children, parents, or parent proxies (i.e. parents' perception of their children's quality of life). Scores could range from 0 (worst quality of life) to 100 (best quality of l... · people with intermittent exotropia, aged less than 11 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |
Prism adaptation test with eye muscle surgery vs eye muscle surgery alone Motor alignment at near fixation Measured using PACT at 6 months · people with intermittent exotropia, aged 5 to 49 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |
Prism adaptation test with eye muscle surgery vs eye muscle surgery alone Stereoacuity at near · people with intermittent exotropia, aged 5 to 49 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |
Prism adaptation test with eye muscle surgery vs eye muscle surgery alone Stereoacuity at distance Measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged 5 to 49 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |
Prism adaptation test with eye muscle surgery vs eye muscle surgery alone Motor alignment at distance fixation Measured using PACT at 6 months · people with intermittent exotropia, aged 5 to 49 years Interventions for intermittent exotropia (2021) · Cochrane | no estimate extracted | NR | No studies |