Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Index pricing vs no index pricing
Healthcare utilisation · Norwegian citizens taking one of the following drugs: citalopram (depression), omeprazol (antiulcer), cetirizin…
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Index pricing vs no index pricing
Health outcomes · Norwegian citizens taking one of the following drugs: citalopram (depression), omeprazol (antiulcer), cetirizin…
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Index pricing vs no index pricing
Adverse events · Norwegian citizens taking one of the following drugs: citalopram (depression), omeprazol (antiulcer), cetirizin…
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Index pricing vs no index pricing
CI: Confidence interval · Norwegian citizens taking one of the following drugs: citalopram (depression), omeprazol (antiulcer), cetirizin…
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Maximum prices vs no maximum prices
Drug prices · Patients taking statins
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Maximum prices vs no maximum prices
Healthcare utilisation · Patients taking statins
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Maximum prices vs no maximum prices
Health outcomes · Patients taking statins
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Maximum prices vs no maximum prices
Drug use · Patients taking statins
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Maximum prices vs no maximum prices
Adverse events · Patients taking statins
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Maximum prices vs no maximum prices
CI: Confidence interval · Patients taking statins
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Reference pricing policy vs no reference pricing
Healthcare utilisation · Patients with drug insurance
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Reference pricing policy vs no reference pricing
Health outcomes · Patients with drug insurance
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Reference pricing policy vs no reference pricing
Adverse events · Patients with drug insurance
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Index pricing vs no index pricing
Drug expenditures · Norwegian citizens taking one of the following drugs: citalopram (depression), omeprazol (antiulcer), cetirizin…
Pharmaceutical policies: effects of reference pricing, other pricing, and purchasing policies (2014) · Cochrane
no estimate extractedNRNo studies
Cyst aspiration vs conservative management
Live birth rate · women with subfertility
Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane
no estimate extractedNRNo studies
Cyst aspiration vs conservative management
Adverse events rate · women with subfertility
Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol 100‐300 mg daily vs febuxostat 80 mg daily
Pain reduction ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol 100‐300 mg daily vs febuxostat 80 mg daily
Function ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol 100‐300 mg daily vs febuxostat 80 mg daily
Tophus regression · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Pain reduction ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Function ‐ not measured · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Tophus regression ‐ not reported · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs benzbromarone
Serious adverse effects · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Function · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Allopurinol vs placebo
Tophus regression · people with chronic gout
Allopurinol for chronic gout (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Complications of diabetes mellitus · ethnic minority groups with type 2 diabetes mellitus
Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
All‐cause and specific mortality · ethnic minority groups with type 2 diabetes mellitus
Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events · ethnic minority groups with type 2 diabetes mellitus
Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus (2014) · Cochrane
no estimate extractedNRNo studies
Paroxetine vs citalopram
Failure to remit at endpoint · patients with depression
Paroxetine versus other anti‐depressive agents for depression (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 2. ARIPIPRAZOLE vs QUETIAPINE
General functioning ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 2. ARIPIPRAZOLE vs QUETIAPINE
Service use ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 3. ARIPIPRAZOLE vs RISPERIDONE
Quality of life ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 3. ARIPIPRAZOLE vs RISPERIDONE
General functioning ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 3. ARIPIPRAZOLE vs RISPERIDONE
Service use ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 4. ARIPIPRAZOLE vs ZIPRASIDONE
Quality of life ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 4. ARIPIPRAZOLE vs ZIPRASIDONE
General functioning ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 4. ARIPIPRAZOLE vs ZIPRASIDONE
Service use ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 5. ARIPIPRAZOLE vs OLANZAPINE
General functioning ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 5. ARIPIPRAZOLE vs OLANZAPINE
Service use ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 1. ARIPIPRAZOLE vs CLOZAPINE
General functioning ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
COMPARISON 1. ARIPIPRAZOLE vs CLOZAPINE
Service use ‐ not measured · patients with schizophrenia
Aripiprazole versus other atypical antipsychotics for schizophrenia (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
"Moderate" benefit At least 30% reduction in pain · Adults with cancer pain
Codeine, alone and with paracetamol (acetaminophen), for cancer pain (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Proportion below 30/100 mm on VAS · Adults with cancer pain
Codeine, alone and with paracetamol (acetaminophen), for cancer pain (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Patient Global Impression of Change much or very much improved · Adults with cancer pain
Codeine, alone and with paracetamol (acetaminophen), for cancer pain (2014) · Cochrane
no estimate extractedNRNo studies
Alpha blocker vs placebo or control
Need for prostatic surgery ‐ not reported · acute urinary retention in adult men
The role of alpha blockers prior to removal of urethral catheter for acute urinary retention in men (2014) · Cochrane
no estimate extractedNRNo studies
Alpha blocker vs placebo or control
Condition‐specific QoL ‐ not reported · acute urinary retention in adult men
The role of alpha blockers prior to removal of urethral catheter for acute urinary retention in men (2014) · Cochrane
no estimate extractedNRNo studies
Alpha blocker vs placebo or control
Cost effectiveness ‐ not reported · acute urinary retention in adult men
The role of alpha blockers prior to removal of urethral catheter for acute urinary retention in men (2014) · Cochrane
no estimate extractedNRNo studies
Music vs standard care
CI: Confidence interval · mechanically ventilated patients
Music interventions for mechanically ventilated patients (2014) · Cochrane
no estimate extractedNRNo studies
Intranasal neostigmine vs placebo
Change in impairment 1 to 14 days after the start of treatment ‐ not reported · people with myasthenia gravis
Acetylcholinesterase inhibitor treatment for myasthenia gravis (2014) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Objective physiological measures
Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps (2014) · Cochrane
no estimate extractedNRNo studies