Cochrane · systematic review · CD006986

Acetylcholinesterase inhibitor treatment for myasthenia gravis

Mehndiratta, MM, Pandey, S, Kuntzer, T · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Neuromuscular2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
2
No studies
1
Included studies
NR
No studies 1 · 33.3%Ungraded 0 · 0%Very low 2 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Intranasal neostigmine compared with placebo for myasthenia gravis

Population: people with myasthenia gravis
3 questions
OutcomeEffectEvidenceStatus / GRADE
Improved muscle function various methods1
Intranasal neostigmine vs placebo
no estimate extracted10 participantsVery low
Downgraded: imprecision
Adverse events
Intranasal neostigmine vs placebo
no estimate extracted1 study · 20 participantsVery low
Downgraded: imprecision
Change in impairment 1 to 14 days after the start of treatment ‐ not reported
Intranasal neostigmine vs placebo
no estimate extractedNRNo studies