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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

15,213 questions in 2,394 reviews

current versions
No studies 15,213 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Nebulised antibiotics vs IV antibiotics
Quality of life · people with cystic fibrosis experiencing a pulmonary exacerbation
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (2015) · Cochrane
no estimate extractedNRNo studies
Decision aids for informed consent vs standard informed consent
Accurate risk perception · people considering taking part in clinical trials
Decision aids for people considering taking part in clinical trials (2015) · Cochrane
no estimate extractedNRNo studies
Decision aids for informed consent vs standard informed consent
Values based decision · people considering taking part in clinical trials
Decision aids for people considering taking part in clinical trials (2015) · Cochrane
no estimate extractedNRNo studies
Decision aids for informed consent vs standard informed consent
Recognition that a decision needs to be made · people considering taking part in clinical trials
Decision aids for people considering taking part in clinical trials (2015) · Cochrane
no estimate extractedNRNo studies
Decision aids for informed consent vs standard informed consent
Involvement in decision · people considering taking part in clinical trials
Decision aids for people considering taking part in clinical trials (2015) · Cochrane
no estimate extractedNRNo studies
Leukoreduced PRBCs vs non‐leukoreduced PRBCs
Non‐infectious complication · Patients receiving RBC transfusion
Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion (2015) · Cochrane
no estimate extractedNRNo studies
Adjunct cognitive behavioural therapy vs adjunct supportive psychotherapy
Global state: Clinically significant improvement · patients with delusional disorder
Treatments for delusional disorder (2015) · Cochrane
no estimate extractedNRNo studies
Adjunct cognitive behavioural therapy vs adjunct supportive psychotherapy
Mental state: Delusions ‐ clinically significant improvement · patients with delusional disorder
Treatments for delusional disorder (2015) · Cochrane
no estimate extractedNRNo studies
Adjunct cognitive behavioural therapy vs adjunct supportive psychotherapy
Service use: Admission · patients with delusional disorder
Treatments for delusional disorder (2015) · Cochrane
no estimate extractedNRNo studies
MET vs sham MET
CI: confidence interval · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs all other therapies
General well‐being · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs all other therapies
Adverse events · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs all other therapies
CI: confidence interval · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs all other therapies
General well‐being · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs all other therapies
Adverse events · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs all other therapies
CI: confidence interval · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs that same intervention alone
General well‐being · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs that same intervention alone
Adverse events · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs that same intervention alone
CI: confidence interval · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs that same intervention alone
General well‐being · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs that same intervention alone
Adverse events · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs other therapies plus that intervention
General well‐being · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs that same intervention alone
CI: confidence interval · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs other therapies plus that intervention
General well‐being · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs other therapies plus that intervention
Adverse events · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs other therapies plus that intervention
CI: confidence interval · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs other therapies plus that intervention
Adverse events · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET plus any intervention vs other therapies plus that intervention
CI: confidence interval · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs sham MET
Functional status · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs sham MET
General well‐being · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
MET vs sham MET
Adverse events · patients with non‐specific low‐back pain (LBP)
Muscle energy technique for non‐specific low‐back pain (2015) · Cochrane
no estimate extractedNRNo studies
TDC vs medical therapy
CI: Confidence interval;HR: hazard ratio · people with patent foramen ovale and a history of cryptogenic stroke or transient ischemic attack
Closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a… (2015) · Cochrane
no estimate extractedNRNo studies
Gabapentin vs placebo
Number of patients with self reported pain relief of 50% or greater (not measured) · patients with pain in Guillain‐Barré syndrome
Pharmacological treatment for pain in Guillain‐Barré syndrome (2015) · Cochrane
no estimate extractedNRNo studies
Methylprednisolone vs placebo
Number of patients with self reported pain relief of 50% or greater (not measured) · patients with Guillain‐Barré syndrome, with varying severities of pain
Pharmacological treatment for pain in Guillain‐Barré syndrome (2015) · Cochrane
no estimate extractedNRNo studies
Gabapentin vs carbamazepine
Number of patients with self reported pain relief of 50% or greater (not measured) · intensive care unit in India
Pharmacological treatment for pain in Guillain‐Barré syndrome (2015) · Cochrane
no estimate extractedNRNo studies
Carbamazepine vs placebo
Number of patients with self reported pain relief of 50% or greater (not measured) · patients with pain in Guillain‐Barré syndrome
Pharmacological treatment for pain in Guillain‐Barré syndrome (2015) · Cochrane
no estimate extractedNRNo studies
L‐acetylcarnitine vs placebo
Outcomes: Behaviour or social performance · people being treated for fragile X syndrome
L‐acetylcarnitine for treating fragile X syndrome (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Participants with a serious adverse event · adults with moderate or severe acute postoperative pain
Single dose oral ibuprofen plus codeine for acute postoperative pain in adults (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Deaths · adults with moderate or severe acute postoperative pain
Single dose oral ibuprofen plus codeine for acute postoperative pain in adults (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy
Outcomesa · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 2: comparison of operation types: late results of needle fasciotomy vs limited fasciectomy
Major outcome group 5 (adverse effects)d · 93 participants (van Rijssen 2012a)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 3: comparison of operation types: firebreak skin grafting vs z‐plasty closure of fasciectomy
Major outcome group 2 (patient satisfaction and other PROM) · 79 participants (Ullah 2009)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 4: refining rehabilitation: three months of postoperative night splinting with hand therapy vs hand therapy alone
Major outcome group 2 (patient satisfaction) · 210 participants with Dupuytren's disease of the fingers in 2 studies (225 digits reported across all studies) (Collis…
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 4: refining rehabilitation: three months of postoperative night splinting with hand therapy vs hand therapy alone
Major outcome group 4 (recurrence) · 210 participants with Dupuytren's disease of the fingers in 2 studies (225 digits reported across all studies) (Collis…
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy
Major outcome group 4 (recurrence) · 125 hands in 121 participants with Dupuytren's disease of the fingers for early outcomes (van Rijssen 2006)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 2: comparison of operation types: late results of needle fasciotomy vs limited fasciectomy
DASH hand function score at 5 years Major outcome group 1 (hand function) (scores between 0 and 100, where 0 represents no impairment in hand function and 100 represents maximum impairment in hand function) · 93 participants (van Rijssen 2012a)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Summary of findings table 2: comparison of operation types: late results of needle fasciotomy vs limited fasciectomy
Major outcome group 3 (early angular outcome)b · 93 participants (van Rijssen 2012a)
Surgery for Dupuytren's contracture of the fingers (2015) · Cochrane
no estimate extractedNRNo studies
Dalteparin vs placebo
Pain duration ‐ not measured · patients with people with sickle cell disease
Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease (2015) · Cochrane
no estimate extractedNRNo studies
Dalteparin vs placebo
The requirement for opiate treatment ‐ not measured · patients with people with sickle cell disease
Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease (2015) · Cochrane
no estimate extractedNRNo studies
Dalteparin vs placebo
Number of serious complications of SCD ‐ not measured · patients with people with sickle cell disease
Low‐molecular‐weight heparins for managing vaso‐occlusive crises in people with sickle cell disease (2015) · Cochrane
no estimate extractedNRNo studies