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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
240 questions in 36 reviews · Dementia and Cognitive Improvement
current versionsNo studies 240 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Nasogastric tubes vs no enteral tube feeding Quality of life · people with severe dementia Enteral tube feeding for people with severe dementia (2021) · Cochrane | no estimate extracted | NR | No studies |
Trazodone vs placebo Quality of life · sleep disturbances in dementia Pharmacotherapies for sleep disturbances in dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Trazodone vs placebo Carer burden, well‐being or quality of life · sleep disturbances in dementia Pharmacotherapies for sleep disturbances in dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Orexin antagonists vs placebo Consolidated sleep time · sleep disturbances in dementia Pharmacotherapies for sleep disturbances in dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Melatonin vs placebo Consolidated sleep time · sleep disturbances in dementia Pharmacotherapies for sleep disturbances in dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Orexin antagonists vs placebo Quality of life · sleep disturbances in dementia Pharmacotherapies for sleep disturbances in dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Melatonin vs placebo Quality of life · sleep disturbances in dementia Pharmacotherapies for sleep disturbances in dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Trazodone vs placebo Consolidated nocturnal sleep time · sleep disturbances in dementia Pharmacotherapies for sleep disturbances in dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient rehabilitation) vs conventional rehabilitation Health‐related quality of life · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient and community rehabilitation) vs conventional rehabilitation Cognitive function · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient and community rehabilitation) vs conventional rehabilitation Behaviour · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient and community rehabilitation) vs conventional rehabilitation Pain · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Geriatrician‐led inpatient management vs orthopaedic‐led inpatient management Health‐related quality of life · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Geriatrician‐led inpatient management vs orthopaedic‐led inpatient management Behaviour · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Geriatrician‐led inpatient management vs orthopaedic‐led inpatient management Pain · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient rehabilitation) vs conventional rehabilitation Cognitive function · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient rehabilitation) vs conventional rehabilitation Behaviour · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient rehabilitation) vs conventional rehabilitation Pain · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Interdisciplinary enhanced rehabilitation (inpatient and community rehabilitation) vs conventional rehabilitation Health‐related quality of life · adults with dementia following hip fracture surgery Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery (2020) · Cochrane | no estimate extracted | NR | No studies |
Other NSAIDs vs placebo Activities of daily living · cognitively healthy older adults Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Other NSAIDs vs placebo Health‐related quality of life · cognitively healthy older adults Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
NSAIDs (celecoxib) vs placebo Incidence of dementia · older people with age‐related memory loss Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
NSAIDs (celecoxib) vs placebo Mortality · older people with age‐related memory loss Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
NSAIDs (celecoxib) vs placebo Activities of daily living · older people with age‐related memory loss Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
NSAIDs (celecoxib) vs placebo Health‐related quality of life · older people with age‐related memory loss Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Cognitive decline from baseline · people with MCI Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life · people with MCI Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Aspirin vs placebo Cognitive decline from baseline · cognitively healthy older adults Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Aspirin vs placebo Health‐related quality of life · cognitively healthy older adults Aspirin and other non‐steroidal anti‐inflammatory drugs for the prevention of dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Overall BPSD (multidomain) – not assessed · dementia Simulated presence therapy for dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Anxiety ‐ not measured · dementia Simulated presence therapy for dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life ‐ not measured · dementia Simulated presence therapy for dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dropouts ‐ not measured · dementia Simulated presence therapy for dementia (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life at the end of the intervention period · cognitively healthy people in late life Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Number of participants experiencing 1 or more serious adverse events at the end of the intervention period · cognitively healthy people in late life Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life at the end of the intervention period · cognitively healthy people in late life Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Number of participants experiencing 1 or more serious adverse events at the end of the intervention period · cognitively healthy people in late life Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Global cognitive function measured at the end of the intervention period · cognitively healthy people in late life Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively… (2020) · Cochrane | no estimate extracted | NR | No studies |
Benzodiazepines (lorazepam) vs placebo Length of delirium episode · end‐of‐life patients with advanced cancer and an episode of agitated delirium Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive… (2020) · Cochrane | no estimate extracted | NR | No studies |
Benzodiazepines (lorazepam) vs antipsychotics (haloperidol) Length of delirium episode · adult AIDS patients with delirium Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive… (2020) · Cochrane | no estimate extracted | NR | No studies |
Benzodiazepines (lorazepam) vs antipsychotics (haloperidol) Length of hospital admission · adult AIDS patients with delirium Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive… (2020) · Cochrane | no estimate extracted | NR | No studies |
Benzodiazepines (lorazepam) vs placebo Any adverse event · end‐of‐life patients with advanced cancer and an episode of agitated delirium Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive… (2020) · Cochrane | no estimate extracted | NR | No studies |
Benzodiazepines (lorazepam) vs antipsychotics (chlorpromazine) Length of delirium episode · adult AIDS patients with delirium Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive… (2020) · Cochrane | no estimate extracted | NR | No studies |
Benzodiazepines (lorazepam) vs antipsychotics (chlorpromazine) Length of hospital admission · adult AIDS patients with delirium Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Binary outcomes · vascular dementia, mild‐to‐moderate severity Memantine for dementia (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Binary outcomes · Alzheimer's disease (AD), moderate‐to‐severe Memantine for dementia (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life · vascular dementia Cerebrolysin for vascular dementia (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Caregiver burden · vascular dementia Cerebrolysin for vascular dementia (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Binary outcomes · vascular dementia Cerebrolysin for vascular dementia (2019) · Cochrane | no estimate extracted | NR | No studies |
Single‐component hydration intervention vs control Prevalence of delirium Not measured · people at risk of delirium in institutional long‐term care Interventions for preventing delirium in older people in institutional long‐term care (2019) · Cochrane | no estimate extracted | NR | No studies |