What do systematic reviews say?

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Muscle pain when chewing · People with temporomandibular disorders (TMD)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Frequency of pain episodes · children and young adults with SCD

Sensory functions and pain · adults with traumatic brain injury with spasticity in their arms (1 study) or calves (1 study)

Sensory functions and pain · children/young people aged 4‐18 years with traumatic brain injury and with 'mild to severe spastic tetraparesis' (weakness) in all limbs

Sensory functions and pain · adults with traumatic brain injury with spasticity in their arms and legs

Phantom limb pain frequency · people with transtibial amputation due to peripheral arterial disease or diabetes

Phantom limb pain frequency · people with transtibial amputation due to peripheral arterial disease or diabetes

Overall pain at 12 months  · Patients with symptomatic endometriosis following surgery

Overall pain at 12 months Â

Sustained pain‐free at 24 h · adults with migraine headache ‐ moderate or severe pain

Sustained pain‐free at 24 h · adults with migraine headache ‐ moderate or severe pain

Sustained pain‐free at 24 h · migraine headache ‐ moderate or severe pain

Relief of pain · Adults over 18 years presenting with a single tooth with a clinical diagnosis of irreversible pulpitis