What do systematic reviews say?

Adverse events: dizziness/vertigo/balance problems · children with chronic suppurative otitis media

Adverse events, including infectious complications · Women undergoing ART (IVF, ICSI, or frozen embryo transfer)

Discontinuation of study drug due to adverse events · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

Specific adverse events: haemorrhage · women with recurrent or FIGO stage IVB cervical cancer

Adverse events: need for reoperation/ reimplantation · adults with chronic pain

Adverse effect: clinically important adverse effect of intervention ‐ as defined by individual studies · patients with schizophrenia

Total number of serious adverse events not measured · patients with osteoarthritis

Proportion of people with ≥ 1 serious adverse events · participants with unresectable hepatocellular carcinoma

Proportion of people with ≥ 1 serious adverse events · participants with unresectable hepatocellular carcinoma

Proportion of people with ≥ 1 serious adverse events · participants with unresectable hepatocellular carcinoma

Harms: adverse events (poorly assessed and reported) · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

Harms: adverse events (poorly assessed and reported) · adults with ADHD (available evidence for participants aged between 25 to 53 years old)

Adverse events: need for reoperation/ reimplantation · adults with chronic pain

Number of children with clinical adverse events (any) · children undergoing neurodiagnostic procedures

Frequency of adverse events at two, six and 12 months · adults with newly diagnosed warm AIHA

Adverse events including suicide and suicide ideation · Informal caregivers of adults with diagnosed illnesses

Adverse events including suicide and suicide ideation · Informal caregivers of adults with diagnosed illnesses

Incidence of adverse events within 30 days of surgery · adults aged ≥ 18 years undergoing elective surgery at any surgical site

Withdrawal due to serious adverse events Not reported · patients with rheumatoid arthritis

Withdrawal due to serious adverse events Not reported · patients with rheumatoid arthritis