Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,032 questions · 3,358 findings · 190 reviews · related questions CL0289

No studies found 599 · 17.8%GRADE not reported 1,759 · 52.4%Very low 612 · 18.2%Low 269 · 8%Moderate 107 · 3.2%High 12 · 0.4%

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Video modelling acclimatisation for LA vs Oral hygiene video

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Intralesional betamethasone vs intralesional injections of triamcinolone acetonide

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Intralesional betamethasone may leads to higher clinical resolution compared with intralesional triamcinolone acetonide (low certainty).

1 finding from 1 review

Clindamycin + SRP vs Metronidazole + SRP

Clinical attachment level (CAL) · Adults with aggressive periodontitis

Clindamycin + SRP showed no clear difference in clinical attachment level (CAL) compared with metronidazole + SRP; GRADE not reported.

3 findings from 1 review

Clindamycin + SRP vs Doxycycline + SRP

Probing pocket depth · Adults with aggressive periodontitis

It is very uncertain whether clindamycin + SRP changes probing pocket depth compared with doxycycline + SRP (very low certainty).

3 findings from 1 review

Amoxicillin + metronidazole + SRP vs SRP

Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)

It is very uncertain whether amoxicillin + metronidazole + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).

3 findings from 1 review

Counter-stimulation or distraction vs Conventional treatment

Completion of dental treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Hypnosis vs Conventional treatment

Acceptance of LA · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

Clobetasol propionate 0.025% microspheres vs Clobetasol propionate 0.025% ointment

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Clobetasol propionate 0.025% microspheres showed no clear difference in clinical resolution compared with clobetasol propionate 0.025% ointment; GRADE not reported.

1 finding from 1 review

No additional acid etching (etch-and-rinse adhesive alone) after Er,Cr:YSGG preparation vs Prior acid etching before etch-and-rinse adhesive after Er,Cr:YSGG preparation

Incidence of microleakage · Er,Cr:YSGG laser-prepared cavities restored with etch-and-rinse adhesive systems (in vitro)

Prior acid etching with etch-and-rinse adhesives did not significantly change microleakage after Er,Cr:YSGG preparation (RR 1.18, 95% CI 0.63-2.22; ungraded).

1 finding from 1 review

Levofloxacin + SRP vs SRP

Probing pocket depth · Adults with chronic periodontitis

Levofloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

2 findings from 1 review

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Successful LA/painless treatment · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

The review found no eligible studies for this question.

1 finding from 1 review

High-volume evacuation (HVE) vs Conventional dental suction (low-volume evacuator / saliva ejector)

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling at 40 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with conventional dental suction (low-volume evacuator / saliva ejector) (very low certainty).

1 finding from 1 review

Hypnosis vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether hypnosis changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

Amoxicillin + metronidazole + SRP vs SRP

Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)

Amoxicillin + metronidazole + SRP led to lower percentage of closed pockets compared with SRP; GRADE not reported.

3 findings from 1 review

Clindamycin + SRP vs SRP

Probing pocket depth · Adults with aggressive periodontitis

It is very uncertain whether clindamycin + SRP changes probing pocket depth compared with SRP (very low certainty).

3 findings from 1 review