Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in probing depth (PD) (mm) compared with OFD (open flap debridement) alone (very low certainty).
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD)… changes change in probing depth (PD) (mm) compared with OFD + BG (open flap debridement + bone graft) (very low certainty).
3 findings from 1 review
MD 0.54 [0.33, 0.75]
17 studies · 569 participants
Very low
MD 0.62 [0.30, 0.94]
11 studies · 272 participants
GRADE not reported
MD 0.50 [0.31, 0.69]
10 studies · 381 participants
GRADE not reported
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in probing depth (PD) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.92 [-0.02, 1.86]
7 studies · 248 participants
Very low
MD 1.07 [-0.71, 2.86]
3 studies · 134 participants
GRADE not reported
MD 0.68 [-0.66, 2.02]
5 studies · 164 participants
GRADE not reported
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in probing depth (PD) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in probing pocket depth (PPD) compared with guided tissue regeneration (GTR) with barriers (low certainty).
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing pocket depth (PPD) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher change in probing depth (probing depth reduction) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.21 [0.53, 1.88]
11 studies
GRADE not reported
Change in probing pocket depth (PPD) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher change in probing depth (probing depth reduction) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.24 [0.89, 1.59]
2 studies
GRADE not reported
Change in probing pocket depth (PPD) · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to non-surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review
Change in probing pocket depth (PPD) · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review