Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,252 questions · 2,353 findings · 210 reviews · Neonatal

No studies found 432 · 18.4%GRADE not reported 99 · 4.2%Very low 609 · 25.9%Low 737 · 31.3%Moderate 385 · 16.4%High 91 · 3.9%

Intravenous fluid supplementation vs no fluid supplementation

Proportion of infants who required exchange transfusion · newborn infants with unconjugated hyperbilirubinaemia undergoing phototherapy

Intravenous fluid supplementation may leads to lower proportion of infants who required exchange transfusion compared with no fluid supplementation (low certainty).

1 finding from 1 review

Intervention not reported

Catheter‐associated thrombosis necessitating removal of catheter (during intervention period) · newborn infants

The intervention showed no clear difference in catheter‐associated thrombosis necessitating removal of catheter… (low certainty).

1 finding from 1 review

Intervention not reported

Bayley MDI at 12 months post‐term · Preterm infants on enteral feed

The intervention showed no clear difference in bayley MDI at 12 months post‐term (low certainty).

1 finding from 1 review

Intervention not reported

Bayley PDI at 12 months post‐term · Preterm infants on enteral feed

The intervention showed no clear difference in bayley PDI at 12 months post‐term (low certainty).

1 finding from 1 review

Intervention not reported

Weight at 12 months post‐term (kg) · Preterm infants on enteral feed

The intervention showed no clear difference in weight at 12 months post‐term (kg) (low certainty).

1 finding from 1 review

Intervention not reported

Length at 12 months post‐term (cm) · Preterm infants on enteral feed

The intervention showed no clear difference in length at 12 months post‐term (cm) (low certainty).

1 finding from 1 review

Intervention not reported

Head circumference at 12 months post‐term (cm) · Preterm infants on enteral feed

The intervention showed no clear difference in head circumference at 12 months post‐term (cm) (low certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in chronic lung disease (oxygen use at 28 days in survivors) compared with no supplementation (moderate certainty).

2 findings from 1 review