Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,293 questions · 2,395 findings · 172 reviews · Gut

No studies found 420 · 17.5%GRADE not reported 60 · 2.5%Very low 821 · 34.3%Low 602 · 25.1%Moderate 397 · 16.6%High 95 · 4%

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term mortality (time‐to‐event outcome): radiotherapy versus surgery All‐cause mortality for the duration of · patients with oesophageal cancer

It is very uncertain whether non‐surgical changes long‐term mortality (time‐to‐event outcome): radiotherapy versus… compared with surgical treatment of oesophageal cancer (primary outcomes) (very low certainty).

1 finding from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Proportion of participants with 1 or more serious adverse events according to International Conference on Harmonisation Good Clinical Practice (ICH‐GCP) · patients with oesophageal cancer

It is very uncertain whether non‐surgical changes proportion with a serious adverse event within 3 months Serious… compared with surgical treatment of oesophageal cancer (primary outcomes) (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

Short‐term mortality · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes short‐term mortality compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

New onset of diabetes · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes new‐onset diabetes compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

Pancreatic exocrine insufficiency · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes pancreatic exocrine insufficiency compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

Long‐term mortality · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes long‐term mortality compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

Adverse events (proportion) · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes adverse events (proportion) compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review

Duodenum‐preserving pancreatic resection vs pancreaticoduodenectomy

Adverse events (number of adverse events) · people requiring surgery for chronic pancreatitis

It is very uncertain whether duodenum‐preserving pancreatic resection changes adverse events (number of adverse events) compared with pancreaticoduodenectomy (very low certainty).

1 finding from 1 review