Question · asked by 1 review
Pregabalin vs placebo: Adverse events
- Population
- patients with chronic pancreatitis and pancreatic pain
- Intervention
- Pregabalin
- Comparison
- placebo
- Outcome
- Adverse events
Pregabalin probably leads to higher adverse events compared with placebo (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pregabalin vs placebo Adverse events · patients with chronic pancreatitis and pancreatic pain Pregabalin probably leads to higher adverse events compared with placebo (moderate certainty). Pregabalin for decreasing pancreatic pain in chronic pancreatitis (2016) · Cochrane Headline outcomes only | RR 1.71 [1.2, 2.43] | 1 study · 64 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pregabalin for decreasing pancreatic pain in chronic pancreatitis 2016 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Pregabalin vs placebo · children and adolescents with chronic non‐cancer pain · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.