Findings

What do systematic reviews say?

1,923 questions · 1,956 findings · 143 reviews · Musculoskeletal

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No studies found 555 · 28.4%GRADE not reported 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%

Intervention not reported

Disability ‐ not measured · patients with chronic (mean 23 months) lateral elbow pain

The review found no eligible studies for this question.

1 finding from 1 review

Surgery for lateral elbow pain 2011 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pulmonary Methotrexate pneumonitis · patients with inflammatory arthritis on methotrexate

1 finding from 1 review

Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving… 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 27 participants
Moderate

Intervention not reported

Hepatic Liver histology/hepatic enzyme abnormalities2 · patients with inflammatory arthritis on methotrexate

1 finding from 1 review

Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving… 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 272 participants
Low

Intervention not reported

Renal Glomerular and tubular injury · patients with inflammatory arthritis on methotrexate

1 finding from 1 review

Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving… 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 30 participants
Low

Intervention not reported

Haematological Thrombocytopenia · patients with inflammatory arthritis on methotrexate

1 finding from 1 review

Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving… 2011 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 1 participants
Moderate

Intervention not reported

Withdrawal due to adverse events Methotrexate discontinuation · patients with inflammatory arthritis on methotrexate

1 finding from 1 review

Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving… 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 632 participants
Low

Intervention not reported

All adverse events · patients with inflammatory arthritis on methotrexate

1 finding from 1 review

Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving… 2011 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 283 participants
Moderate

Tricyclic antidepressants vs control

Pain < 1 week VAS scale 0 to 100 mm · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Tricyclic antidepressants vs control

Pain 1 to 6 weeks Any pain measurement scale · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 482 participants
Very low

Tricyclic antidepressants vs control

Pain > 6 weeks Any pain measurement scale · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 368 participants
Very low

Tricyclic antidepressants vs control

Functional Status Health Assessment Questionnaire (HAQ) scale 0 to 3 · patients with pain management in rheumatoid arthritis

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Low

Tricyclic antidepressants vs control

Withdrawals due to adverse events · patients with pain management in rheumatoid arthritis

It is very uncertain whether tricyclic antidepressant changes number of Withdrawals due to Adverse Events patient interview compared with control (very low certainty).

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
RR 0.98 [0.59, 1.64]
6 studies · 455 participants
Very low

Tricyclic antidepressants vs control

Total number of adverse events patient interview · patients with pain management in rheumatoid arthritis

It is very uncertain whether tricyclic antidepressant changes total number of adverse events patient interview compared with control (very low certainty).

1 finding from 1 review

Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only
RR 1.83 [1.01, 3.3]
6 studies · 455 participants
Very low

Intervention not reported

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1835 participants
Low

Intervention not reported

Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with knee osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1398 participants
High

Intervention not reported

Adverse events · Patients with knee osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Side effects of acupuncture‐Bruising and bleeding at injection site · Patients with knee osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Function (short term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1767 participants
Low

Intervention not reported

Pain (long term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1399 participants
High

Intervention not reported

Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1398 participants
High