Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,501 questions · 1,558 findings · 115 reviews · Vascular

No studies found 346 · 22.2%GRADE not reported 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Endovenous laser ablation may leads to lower recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence · people requiring intervention for short saphenous vein varices

Endovenous laser ablation showed no clear difference in clinical evidence of recurrence after 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Amputation · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon showed no clear difference in amputation compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Primary vessel patency · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon leads to higher primary vessel patency compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Target lesion revascularization · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon may leads to lower target lesion revascularization compared with uncoated balloon angioplasty at 12 months (low certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Binary restenosis · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon probably leads to lower binary restenosis compared with uncoated balloon angioplasty at 12 months (moderate certainty).

1 finding from 1 review

Drug‐eluting balloon vs uncoated balloon angioplasty at 12 months

Death · people with peripheral arterial disease of the lower limbs

Drug‐eluting balloon showed no clear difference in death compared with uncoated balloon angioplasty at 12 months (high certainty).

1 finding from 1 review