Cochrane · systematic review · CD001367
Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism
Middeldorp, S, Prins, MH, Hutten, BA · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Long‐term or short‐term treatment with vitamin K antagonists for patients with venous thromboembolism
Population: patients with venous thromboembolism
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Incidence of recurrent VTE | RR 0.2 [0.11, 0.38] | 10 studies · 3536 participants | High |
Incidence of major bleeding | RR 3.44 [1.22, 9.74] | 6 studies · 1350 participants | Moderate |
Mortality | RR 0.69 [0.35, 1.34] | 4 studies · 1049 participants | Moderate Downgraded: imprecision |