Patient satisfaction · People who had received fixed appliance orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review
Not measured
0 studies
No studies found
Oral health-related quality of life · Adolescents (10-19 years)
Safe housing and favorable household conditions are associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).
1 finding from 1 review
Plaque · Orthodontic patients undergoing comprehensive treatment (late mixed or permanent dentition, no active caries)
In randomized trials, clear aligners probably reduce plaque accumulation versus fixed appliances, though the subgroup estimate is imprecise and its CI crosses no effect (SMD -1.79, 95% CI -3.63 to 0.04; moderate certainty).
6 findings from 1 review
Show 3 more findings
Intervention not reported
Quality of life
1 finding from 1 review
Cathepsin K (CT-K) presence/activity · Human ex vivo carious dentin (mostly coronal), natural caries lesions
Cathepsin K may be increased in carious dentin (one study), but no certainty rating was assigned (ungraded).
1 finding from 1 review
Higher intensity of immunodetection of CT-K was registered in carious dentin than in sound dentin (Vidal et al., 2014); GRADE was not applied to CT-K.
1 study · 10 participants
GRADE not reported
Remineralization / reduction in lesion severity (change in QLF, laser fluorescence, or lesion area) · Patients with white spot lesions / early caries lesions (WSLs/ECLs), including orthodontic and non-orthodontic lesions, active caries…
Resin infiltration was significantly better than fluoride varnish (SMD -0.70, 95% CI -1.18 to -0.21); certainty of evidence not assessed (no GRADE).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing pulpotomy
The effect of MTA versus CH after pulpotomy is uncertain (low certainty).
1 finding from 1 review
Disease-free survival · Adults with oral cavity or oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects on oral health: Gingival Index (lower arch) · People who had received fixed appliance orthodontic treatment
It is very uncertain whether part-time clear plastic (removable) retainer changes adverse effects on oral health: Gingival Index (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).
1 finding from 1 review
MMP-13 presence/activity · Human coronal carious dentin and sound dentin
MMP-13 may be increased in carious dentin compared with sound dentin (very low certainty).
1 finding from 1 review
Restoration color, marginal staining and luster (esthetics) · Children with deep occlusal caries in young permanent first molars (indirect pulp capping)
RMGIC gave significantly better restoration esthetics than SDF, which caused black staining (p=0.03; ungraded).
1 finding from 1 review
Baraka et al. (2022): significant differences in restoration color, marginal staining and luster favoring RMGIC over both SDF groups (p=0.03); SDF caused black staining that darkened over time.
1 study · 49 participants
GRADE not reported
Patient satisfaction (measured by patient satisfaction or aesthetic scales) · People who had received fixed appliance orthodontic treatment
It is very uncertain whether fibre-reinforced composite fixed (bonded) retainer changes patient satisfaction: aesthetics (VAS 0-10 cm, lower arch) compared with multistrand / spiral wire fixed (bonded) retainer (very low certainty).
1 finding from 1 review
Predictive performance for root caries increment (negative likelihood ratio, LR-) · Older adults (aged 52-95; mean 52-73) at risk of root caries increment
The single root-caries validation study (Hayes 2017) showed LR- of 0.34-0.41, above the useful rule-out threshold; no pooled estimate; ungraded.
2 findings from 1 review
Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth undergoing pulpotomy
The two trials of PRF versus MTA for success gave contradictory results and were not pooled (ungraded).
1 finding from 1 review
Caries/restoration status in permanent molars · Children with dental caries in permanent (first) molars
SDF gave significantly better caries/restoration outcomes than ART over 9 months in children's permanent molars (p=0.004; ungraded).
1 finding from 1 review
Satyarup et al. (2022): 38% SDF vs ART; SDF group 5.6% carious teeth with partly lost restorations vs ART 16.7% carious with partly lost and 8.9% carious with completely lost restorations (p=0.004, favoring SDF).
1 study · 190 participants
GRADE not reported
new root-surface carious lesions or restorations · community-dwelling older adults with root caries
SDF had a 62% preventative fraction; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
MMP-2 expression/activity · Human ex vivo carious dentin (head/neck radiotherapy)
MMP-2 showed no difference between irradiated and non-irradiated carious dentin (one study; ungraded).
1 finding from 1 review
No significant difference in MMP-2 (gelatinase) expression or activity between irradiated and non-irradiated groups (Gomes-Silva et al., 2017a); GRADE not separately applied to this comparison.
1 study · 36 participants
GRADE not reported
New coronal caries in permanent molars (caries prevention) · Children with dental caries in permanent (first) molars
NaF gave a 48% prevented fraction (fissure site) vs water (p<0.002; ungraded).
3 findings from 1 review
Prevented Fraction 48
1 study · 501 participants
GRADE not reported
Prevented Fraction 47
1 study · 141 participants
GRADE not reported
Prevented Fraction 41
1 study · 501 participants
GRADE not reported
Patient satisfaction: discomfort/pain (lower arch) · People who had received fixed appliance orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review