Question · asked by 1 review
Platelet-rich fibrin (PRF) graft vs Mineral trioxide aggregate (MTA): Overall success (composite of clinical and radiographic success)
- Population
- Patients with carious pulp exposure in immature permanent teeth undergoing pulpotomy
- Intervention
- Platelet-rich fibrin (PRF) graft
- Comparison
- Mineral trioxide aggregate (MTA)
- Outcome
- Overall success (composite of clinical and radiographic success)
The two trials of PRF versus MTA for success gave contradictory results and were not pooled (ungraded).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Platelet-rich fibrin (PRF) vs Mineral trioxide aggregate (MTA) Clinical and radiographic success (composite) · Patients with carious pulp exposure in immature permanent teeth undergoing pulpotomy · ≥6 months follow-up, Dental/endodontic clinical settings across multiple countries (university, hospital, specialist and general dental practice); permanent teeth with carious pulp exposure The two trials of PRF versus MTA for success gave contradictory results and were not pooled (ungraded). Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious… (2023) All outcomes | PRF vs MTA was investigated in 2 RCTs (Alawwad 2020; Keswani 2014) for the primary outcome; the two trials provided contradictory evidence and differed in risk of bias, so were not pooled. Weak evidence. | 2 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Comparative efficacy of materials used in patients undergoing pulpotomy or direct pulp capping in carious teeth: A systematic review and… 2023 All outcomes | 28 February 2021 (from inception to 28/2/2021) | 21 | Critically Low / Critically Low |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Platelet-rich fibrin (PRF) graft vs Calcium hydroxide (CH) · Mature permanent teeth with irreversible pulpitis and carious pulp exposure (treated… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.