Findings

What do systematic reviews say?

1,444 questions · 1,518 findings · 135 reviews · Infectious Diseases

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No studies found 135 · 8.9%GRADE not reported 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%

Azithromycin vs ciprofloxacin

Duration of diarrhoea · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 375 participants
Moderate

Azithromycin vs ciprofloxacin

Stool volume · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 195 participants
Low

Azithromycin vs ciprofloxacin

Bacteriological failure · Adults and children with cholera diarrhoea

Azithromycin may leads to lower bacteriological failure compared with ciprofloxacin (low certainty).

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
RR 0.23 [0.16, 0.34]
2 studies · 375 participants
Low

Azithromycin vs erythromycin

Duration of diarrhoea · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 179 participants
Moderate

Intervention not reported

Patients still unwell at day 4 to 7 · People with fever

The intervention showed no clear difference in patients still unwell at day 4 to 7 (low certainty).

1 finding from 1 review

Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings 2014 · Cochrane Headline outcomes only
RR 0.9 [0.69, 1.17]
5 studies · 6990 participants
Low

Intervention not reported

Patients prescribed antimalarials · People with fever

The intervention probably leads to lower patients prescribed antimalarials (moderate certainty).

1 finding from 1 review

Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings 2014 · Cochrane Headline outcomes only
RR 0.62 [0.52, 0.73]
7 studies · 17287 participants
Moderate

Intervention not reported

Patients prescribed antibiotics · People with fever

1 finding from 1 review

Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 13573 participants
Very low

Intervention not reported

Patients with microscopically confirmed malaria not receiving antimalarials · People with fever

The intervention showed no clear difference in patients with microscopically confirmed malaria not receiving… (low certainty).

1 finding from 1 review

Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings 2014 · Cochrane Headline outcomes only
RR 1.21 [0.64, 2.28]
1 study · 1280 participants
Low

Intervention not reported

Peripheral health centre with a prior probability of disease of 40% · Patients suspected to have visceral leishmaniasis disease 1

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1468 participants
High

Intervention not reported

Referral centre with a prior probability of disease of 60% · Patients suspected to have visceral leishmaniasis disease 1

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1468 participants
High

Intervention not reported

CI: confidence interval · Patients suspected to have visceral leishmaniasis disease 1

The review found no eligible studies for this question.

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Peripheral health centre with a prior probability of disease of 40% · Patients suspected to have visceral leishmaniasis disease 1

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1692 participants
High

Intervention not reported

Referral centre with a prior probability of disease of 60% · Patients suspected to have visceral leishmaniasis disease 1

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1692 participants
High

Intervention not reported

CI: confidence interval · Patients suspected to have visceral leishmaniasis disease 1

The review found no eligible studies for this question.

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Peripheral health centre with a prior probability of disease of 40% · Patients suspected to have visceral leishmaniasis disease 1

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1374 participants
High

Intervention not reported

Referral centre with a prior probability of disease of 60% · Patients suspected to have visceral leishmaniasis disease 1

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1374 participants
High

Intervention not reported

CI: confidence interval · Patients suspected to have visceral leishmaniasis disease 1

The review found no eligible studies for this question.

1 finding from 1 review

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pre‐referral rectal artesunate vs placebo

All cause mortality · Patients with severe malaria

Pre‐referral rectal artesunate probably leads to lower all cause mortality compared with placebo (moderate certainty).

1 finding from 1 review

Pre‐referral rectal artesunate for severe malaria 2014 · Cochrane Headline outcomes only
RR 0.74 [0.59, 0.93]
1 study · 8050 participants
Moderate

Pre‐referral rectal artesunate vs placebo

Neurodisability · Patients with severe malaria

Pre‐referral rectal artesunate showed no clear difference in neurodisability compared with placebo (low certainty).

1 finding from 1 review

Pre‐referral rectal artesunate for severe malaria 2014 · Cochrane Headline outcomes only
RR 0.68 [0.35, 1.3]
1 study · 17280 participants
Low

Dihydroartemisinin‐piperaquine vs artemether‐lumefantrine (AL)

Treatment failure Day 28 · adults and children with uncomplicated P falciparum malaria

Dihydroartemisinin‐piperaquine leads to lower treatment failure Day 28 compared with artemether‐lumefantrine (high certainty).

1 finding from 1 review

Dihydroartemisinin‐piperaquine for treating uncomplicated Plasmodium falciparum malaria 2014 · Cochrane Headline outcomes only
RR 0.34 [0.3, 0.39]
9 studies · 6200 participants
High