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What do systematic reviews say?

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Evidence found and GRADE certainty

266 questions · 274 findings · 25 reviews · Movement Disorders

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No studies found 13 · 4.7%GRADE not reported 7 · 2.6%Very low 66 · 24.1%Low 66 · 24.1%Moderate 87 · 31.8%High 35 · 12.8%

Opioids vs placebo

Adverse events · RLS

Opioids may leads to higher adverse Events compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Functional abilities Change in TRS part B score (motor tasks).36 points (0 is better) Change in TRS part C score (functional disability), 32 points (0 is better) · patients with essential tremor
1 finding from 1 review

Intervention not reported

Study withdrawal Number of patients withdrawn from the study · patients with essential tremor

It is very uncertain whether the intervention changes study withdrawal Number of patients withdrawn from the study (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events Number of adverse events · patients with essential tremor

It is very uncertain whether the intervention changes adverse events Number of adverse events (very low certainty).

1 finding from 1 review

Virtual reality vs active intervention (short term)

Gait assessment · rehabilitation in Parkinson's disease
3 findings from 1 review