Cochrane · systematic review · CD010916
Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease
Elsner, B, Kugler, J, Pohl, M, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Movement DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Transcranial direct current stimulation (tDCS) versus sham tDCS for patients with idiopathic Parkinson's disease
Population: Patients with idiopathic Parkinson's disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Impairment/ disability Unified Parkinson's Disease Rating Scale (UPDRS; change in global UPDRS score). Scale from: 0 to 199 (lower score means less impairment/disability) Transcranial direct current stimulation (tDCS) vs sham tDCS | no estimate extracted | 2 studies · 45 participants | Very low Downgraded: risk of bias, imprecision |
Off time Self assessment (logfile) Scale from: 0 to 72 (lower score means less impairment/disability) Transcranial direct current stimulation (tDCS) vs sham tDCS | no estimate extracted | 1 study · 25 participants | Very low Downgraded: risk of bias, imprecision |
On time with dyskinesia Self assessment (logfile) Scale from: 0 to 72 (lower score means less impairment/disability) Transcranial direct current stimulation (tDCS) vs sham tDCS | no estimate extracted | 1 study · 25 participants | Very low Downgraded: risk of bias, imprecision |
Gait speed at the end of the intervention phase Measures of timed gait. Scale from: 0 (lower score means less impairment/disability) Transcranial direct current stimulation (tDCS) vs sham tDCS | no estimate extracted | 2 studies · 41 participants | Very low Downgraded: risk of bias, imprecision |
Health‐related quality of life ‐ physical health SF‐ 12v2. Scale from: 0 to 100 (scores less than 50 indicate health above the mean and scores less than 50 indicate health below the mean) Transcranial direct current stimulation (tDCS) vs sham tDCS | no estimate extracted | 1 study · 25 participants | Very low Downgraded: risk of bias, imprecision |
Health‐related quality of life ‐ mental health SF‐12v2. Scale from: 0 to 100 (scores less than 50 indicate health above the mean and scores less than 50 indicate health below the mean) Transcranial direct current stimulation (tDCS) vs sham tDCS | no estimate extracted | 1 study · 25 participants | Very low Downgraded: risk of bias, imprecision |
Safety/ acceptability Dropouts and adverse events (lower rate means better safety/acceptability) Transcranial direct current stimulation (tDCS) vs sham tDCS | no estimate extracted | 4 studies · 101 participants | Very low Downgraded: risk of bias |