Cochrane · systematic review · CD009682

Pregabalin for essential tremor

Bruno, E, Nicoletti, A, Quattrocchi, G, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Movement DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Pregabalin for essential tremor

Population: patients with essential tremor
3 questions
OutcomeEffectEvidenceStatus / GRADE
Functional abilities Change in TRS part B score (motor tasks).36 points (0 is better) Change in TRS part C score (functional disability), 32 points (0 is better)
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Study withdrawal Number of patients withdrawn from the study
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events Number of adverse events
RD 0.181 study · 22 participantsVery low
Downgraded: risk of bias, imprecision