Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
SDF probably makes little to no difference to surface-level caries arrestment versus other methods (moderate certainty).
1 finding from 1 review
Dental caries susceptibility · Institutionalized orphan children (roughly 3 to 18 years)
Primary teeth may carry a higher caries risk than permanent teeth in institutionalized children (RR 1.31), but the difference is not statistically significant (very low certainty).
1 finding from 1 review
Range of mandibular motion · People with temporomandibular disorders (TMD)
Occlusal splint showed no clear difference in range of mandibular motion compared with no treatment or placebo (non-occlusal or transparent-foil placebo…; GRADE not reported.
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
3 findings from 1 review
No studies reported data in this dentition type
0 studies
No studies found
No studies reported data in this dentition type
0 studies
No studies found
MD -0.13 [-0.87, 0.61]
1 study · 309 participants
Very low
Systemic antibiotics without surgical intervention (with or without analgesics) vs Matched placebo without surgical intervention (with or without analgesics)
Outcome not reported · Adults with symptomatic apical periodontitis or acute apical abscess
The review found no eligible studies for this question.
1 finding from 1 review
Dental caries prevalence · Brazilian children under 5 years in primary dentition (BMI classified by WHO 2006 Z-score)
The evidence is very uncertain about the effect of overweight/obesity on caries odds in the primary dentition (WHO 2006 Z-score; very low certainty).
1 finding from 1 review
OR 0.86 [0.60, 1.22]
3 studies
Very low
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional steroid injections changes burning sensation (VAS 0-100) compared with alternative medicinal treatments (very low certainty).
2 findings from 1 review
Dental caries - SNP-based heritability · Japanese adults (present-study cohort)
SNP-based heritability of dental caries was low (h2=0.0258, SE 0.0155); ungraded.
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Caries arrestment at the tooth level · Children and adults without systemic diseases affecting dental health
SDF showed a higher caries-free proportion at the tooth level, but the reported difference was not statistically significant.
1 finding from 1 review
Improvement in range of jaw movement · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
The review found no eligible studies for this question.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
Recessive model (CC vs CT+TT) at FokI(rs10735810) showed no significant association with caries (OR 1.23, 95% CI 0.97-1.55); ungraded.
1 finding from 1 review
Time to alignment · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
Dental caries prevalence · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)
The evidence is very uncertain about the effect of obesity on caries odds in the primary dentition (very low certainty).
1 finding from 1 review
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) showed no clear difference in ANB compared with facemask only (low certainty).
1 finding from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional dexamethasone injections changes burning sensation (VAS 0-100) compared with placebo injections (very low certainty).
2 findings from 1 review
MD -52.00 [-62.04, -41.96]
1 study · 25 participants
Very low
MD -46.00 [-53.44, -38.56]
1 study · 25 participants
Very low
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) led to higher overjet compared with modified tandem appliance; GRADE not reported.
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
Silver diamine fluoride (SDF) showed no clear difference in caries arrest compared with silver nitrate plus fluoride varnish (low certainty).
1 finding from 1 review
Time to alignment · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
The review found no eligible studies for this question.
1 finding from 1 review
Frequency of joint noise · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes frequency of joint noise compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).
1 finding from 1 review