Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,079 questions · 2,112 findings · 171 reviews · Eyes and Vision

No studies found 587 · 27.8%GRADE not reported 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

IPL (with/without MGX) vs no treatment/sham

Dry eye symptoms, measured using the OSDI score (ranging from 0 to 100 units, with a reduction in scores indicating clinical improvement) at 1‐month (with actual · people with meibomian gland dysfunction

It is very uncertain whether IPL (with/without MGX) changes dry eye symptoms, measured using the SPEED score at 3 months of compared with sham or no treatment (with/without MGX) (very low certainty).

1 finding from 1 review

IPL (with/without MGX) vs no treatment/sham

Tear osmolarity, measured in mOsmol/L, at 3 months of · people with meibomian gland dysfunction

IPL (with/without MGX) showed no clear difference in tear osmolarity, measured in mOsmol/L, at 3 months of compared with sham or no treatment (with/without MGX) (low certainty).

1 finding from 1 review

IPL (with/without MGX) vs no treatment/sham

Meibomian gland orifice plugging, at 3 months of · people with meibomian gland dysfunction

It is very uncertain whether IPL (with/without MGX) changes meibomian gland orifice plugging, at 3 months of compared with sham or no treatment (with/without MGX) (very low certainty).

1 finding from 1 review