Cochrane · systematic review · CD013559
Intense pulsed light (IPL) therapy for the treatment of meibomian gland dysfunction
Cote, S, Zhang, AC, Ahmadzai, V, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 71.4%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
IPL (with/without MGX) compared to sham or no treatment (with/without MGX) for the treatment of meibomian gland dysfunction
Population: people with meibomian gland dysfunction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dry eye symptoms, measured using the SPEED score at 3 months of IPL (with/without MGX) vs sham or no treatment (with/without MGX) | MD 0 | NR | Very low Downgraded: risk of bias, imprecision, inconsistency |
Incidence of adverse events at 3 months of IPL (with/without MGX) vs sham or no treatment (with/without MGX) | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision |
Sodium fluorescein TBUT, measured in seconds, at 3 months of IPL (with/without MGX) vs sham or no treatment (with/without MGX) | MD 2.02 | NR | Low Downgraded: risk of bias, imprecision |
NIBUT, measured in seconds, at 3 months of IPL (with/without MGX) vs sham or no treatment (with/without MGX) | MD 5.5 | NR | Very low Downgraded: risk of bias, imprecision |
Tear osmolarity, measured in mOsmol/L, at 3 months of IPL (with/without MGX) vs sham or no treatment (with/without MGX) | no estimate extracted | NR | Low Downgraded: imprecision |
Meibomian gland orifice plugging, at 3 months of IPL (with/without MGX) vs sham or no treatment (with/without MGX) | no estimate extracted | NR | Very low Downgraded: risk of bias, inconsistency |
Corneal sodium fluorescein staining, measured using a validated clinical scale, at 3 months of IPL (with/without MGX) vs sham or no treatment (with/without MGX) | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, inconsistency |