Findings

What do systematic reviews say?

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

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No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

NSAIDs vs combined OCP

Requirement for additional medication · women with primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NSAIDs vs combined OCP

Time off school or work · women with primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Combined OCP vs placebo or no treatment

Pain improvement (assessed as improvement from 1 major category to next) · women with primary dysmenorrhoea

Combined OCP may leads to higher pain improvement (assessed as improvement from 1 major category to… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
RR 1.65 [1.29, 2.1]
6 studies · 717 participants
Low

Combined OCP vs placebo or no treatment

Adverse events · women with primary dysmenorrhoea

Combined OCP probably leads to higher adverse events compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
RR 1.31 [1.2, 1.43]
7 studies · 1025 participants
Moderate

Combined OCP vs placebo or no treatment

Requirement for additional medication · women with primary dysmenorrhoea

Combined OCP may leads to lower requirement for additional medication compared with placebo or no treatment (low certainty).

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
RR 0.63 [0.4, 0.98]
2 studies · 163 participants
Low

Combined OCP vs placebo or no treatment

Time off school or work · women with primary dysmenorrhoea

Combined OCP may leads to lower absence from work or school compared with placebo or no treatment (low certainty).

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
RR 0.63 [0.41, 0.97]
2 studies · 148 participants
Low

Combined low‐dose OCP vs another combined low‐dose OCP

Pain score ( · women with primary dysmenorrhoea

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 106 participants
Low

Combined low‐dose OCP vs another combined low‐dose OCP

Pain improvement · women with primary dysmenorrhoea

Combined low‐dose OCP showed no clear difference in pain improvement compared with another combined low‐dose OCP (moderate certainty).

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
RR 1.06 [0.65, 1.74]
1 study · 326 participants
Moderate

Combined low‐dose OCP vs another combined low‐dose OCP

Adverse events for continuous vs standard regimen OCP · women with primary dysmenorrhoea

Combined low‐dose OCP may leads to higher adverse events for continuous vs standard regimen OCP compared with another combined low‐dose OCP (low certainty).

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
RR 1.11 [1.01, 1.22]
3 studies · 602 participants
Low

Combined low‐dose OCP vs another combined low‐dose OCP

Requirement for additional medication · women with primary dysmenorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Combined oral contraceptive pill for primary dysmenorrhoea 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVF vs expectant management

Live birth rate per woman · women with unexplained subfertility

It is very uncertain whether IVF changes live birth per woman randomised compared with expectant management (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 22 [2.56, 189.37]
1 study · 51 participants
Very low

IVF vs unstimulated IUI

Miscarriage · women with unexplained subfertility

It is very uncertain whether IVF changes miscarriage rate per woman randomised compared with unstimulated IUI (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 1.72 [0.14, 21.25]
1 study · 43 participants
Very low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

Live birth rate per woman · women with unexplained subfertility

IVF showed no clear difference in live birth rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 1.19 [0.87, 1.61]
3 studies · 731 participants
Low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

Clinical pregnancy rate · women with unexplained subfertility

IVF showed no clear difference in clinical pregnancy rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 1.17 [0.85, 1.59]
3 studies · 731 participants
Low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

Multiple pregnancy rate · women with unexplained subfertility

IVF showed no clear difference in multiple pregnancy rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 0.82 [0.38, 1.77]
3 studies · 731 participants
Low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

OHSS · women with unexplained subfertility

It is very uncertain whether IVF changes OHSS rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 6.86 [0.35, 134.59]
1 study · 207 participants
Very low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

Miscarriage · women with unexplained subfertility

It is very uncertain whether IVF changes miscarriage rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 0.31 [0.03, 3.04]
1 study · 207 participants
Very low

IVF vs expectant management

Clinical pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes clinical pregnancy rate per woman randomised compared with expectant management (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 3.24 [1.07, 9.8]
2 studies · 86 participants
Very low

IVF vs expectant management

Multiple pregnancy rate · women with unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVF vs expectant management

OHSS · women with unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found