Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,501 questions · 1,558 findings · 115 reviews · Vascular

No studies found 346 · 22.2%GRADE not reported 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

TNF‐α blockers intervention vs placebo or additional treatment

Adverse effects after treatment initiation: injection site reactions, neutropenia, infections, demyelinating disease, heart failure, malignancy, and induction of autoimmunity. · children diagnosed with Kawasaki disease

The review found no eligible studies for this question.

1 finding from 1 review

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Target lesion revascularization · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes target lesion revascularization (TLR) compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Binary restenosis · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes binary restenosis compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Death · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes death compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Drug‐eluting balloon angioplasty at 6 months vs uncoated balloon angioplasty at 6 months

Improvement ≥ 1 Rutherford category · patients with in‐stent restenosis of the femoropopliteal arteries

It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes improvement ≥ 1 Rutherford category compared with uncoated balloon angioplasty at 6 months (very low certainty).

1 finding from 1 review

Intervention not reported

Pulmonary embolism · Patients hospitalised following acute myocardial infarction

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse effects and complications · Patients hospitalised following acute myocardial infarction

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Deep vein thrombosis (DVT) · Patients hospitalised for surgical procedures1

The intervention leads to lower deep vein thrombosis (DVT) (high certainty).

1 finding from 1 review

Intervention not reported

Proximal DVT · Patients hospitalised for surgical procedures1

The intervention probably leads to lower proximal DVT (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse effects and complications · Patients hospitalised for surgical procedures1

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Deep vein thrombosis (DVT) · Patients hospitalised following acute myocardial infarction

The intervention may leads to lower deep vein thrombosis (DVT) (low certainty).

1 finding from 1 review

Autologous vein vs other graft types

Primary patency ( · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery

Autologous vein may leads to lower primary patency (24 months) compared with other graft types (low certainty).

2 findings from 1 review

Externally supported graft vs unsupported graft

Primary patency ( · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery

The review found no eligible studies for this question.

2 findings from 1 review