Findings

What do systematic reviews say?

996 questions · 1,049 findings · 79 reviews · Dementia and Cognitive Improvement

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No studies found 240 · 22.9%GRADE not reported 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

Vitamin E vs placebo

Quality of life ‐ not measured · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin E vs placebo

All‐cause mortality · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
GRADE not reported

Vitamin E + vitamin C vs placebo

Incidence of dementia ‐ not measured · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin E + vitamin C vs placebo

Cognitive function · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 256 participants
Very low

Vitamin E + vitamin C vs placebo

Episodic memory ‐ not measured · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin E + vitamin C vs placebo

Executive function ‐ not measured · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin E + vitamin C vs placebo

Speed of processing ‐ not measured · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin E + vitamin C vs placebo

Quality of life ‐ not measured · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

B vitamins vs placebo

Cognitive function · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 488 participants
Very low

Vitamin E + vitamin C vs placebo

Mortality ‐ not reported · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

B vitamins vs placebo

Cognitive subdomain: episodic memory measured at the end of · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 397 participants
Moderate

B vitamins vs placebo

Executive function (specific cognitive function) · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 392 participants
Moderate

B vitamins vs placebo

Information processing speed · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 173 participants
Moderate

B vitamins vs placebo

Quality of life · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 138 participants
Moderate

B vitamins vs placebo

Mortality ‐ not reported · MCI

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vitamin E vs placebo

Incidence of dementia due to Alzheimer's disease · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 516 participants
Moderate

Vitamin E vs placebo

Cognitive function · MCI

1 finding from 1 review

Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low

B vitamins vs placebo

Supplementation with beta‐carotene + vit C + vit E Overall cognitive functioning · cognitively healthy people in mid and late life

6 findings from 1 review

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 2556 participants
Moderate
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 317 participants
Low
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 6956 participants
Moderate

Show 3 more findings

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 241 participants
Low
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 3985 participants
Moderate
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 10249 participants
Low

Antioxidants vs placebo

Cognitive function · cognitively healthy people in mid and late life

6 findings from 1 review

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1904 participants
Moderate
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 4052 participants
Moderate

Show 3 more findings

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74 participants
Very low
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Low

Antioxidants vs placebo

Supplementation with beta‐carotene + vit C + vit E Overall cognitive functioning · cognitively healthy people in mid and late life

2 findings from 1 review

Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20536 participants
Moderate
Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1100 participants
Moderate