Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,494 questions · 1,521 findings · 132 reviews · Hepato-Biliary

No studies found 303 · 19.9%GRADE not reported 39 · 2.6%Very low 876 · 57.6%Low 216 · 14.2%Moderate 65 · 4.3%High 22 · 1.4%

Intervention not reported

Overall morbidity (30‐day postoperative; procedure‐ and non‐procedure related) · patients with stones in the gallbladder and common bile duct undergoing laparoscopic cholecystectomy

The intervention showed no clear difference in overall morbidity (30‐day postoperative; procedure‐ and… (low certainty).

1 finding from 1 review

Carvedilol vs beta‐blocker

Upper gastrointestinal bleeding · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes upper gastrointestinal bleeding compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Carvedilol vs beta‐blocker

Non‐serious adverse events · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes non‐serious adverse events compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Carvedilol vs beta‐blocker

Haemodynamic treatment failure · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes haemodynamic treatment failure compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Intervention vs no intervention or control intervention (control)

Serious adverse events (number) ‐ pegylated interferon‐alpha plus ribavirin versus pegylated interferon‐alpha · people with acute hepatitis C infection

It is very uncertain whether intervention changes serious adverse events (proportion) ‐ pegylated interferon‐alpha… compared with no intervention or control intervention (control) (very low certainty).

2 findings from 1 review