Cochrane · systematic review · CD008735

Glucocorticosteroids for infants with biliary atresia following Kasai portoenterostomy

Tyraskis, A, Parsons, C, Davenport, M · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 83.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: infants with biliary atresia
6 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality six months after Kasai portoenterostomy
no estimate extractedNRLow
Downgraded: imprecision
Serious adverse event, two years
no estimate extractedNRLow
Downgraded: imprecision, inconsistency
Health‐related quality of life
no estimate extractedNRNo studies
Infants who did not clear jaundice at six months
no estimate extractedNRLow
Downgraded: imprecision
All‐cause mortality or liver transplantation at two years
no estimate extractedNRLow
Downgraded: imprecision
Subgroup analysis of infants operated on at less than 70 days of age who did not clear their jaundice by six months after Kasai portoenterostomy
no estimate extractedNRLow
Downgraded: imprecision