Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,252 questions · 2,353 findings · 210 reviews · Neonatal

No studies found 432 · 18.4%GRADE not reported 99 · 4.2%Very low 609 · 25.9%Low 737 · 31.3%Moderate 385 · 16.4%High 91 · 3.9%

Dextrose gel vs control

Breastfeeding (exclusive after discharge) ‐ not reported (WHO 2008 definition (yes/no)) · newborn infants with hypoglycaemia

Oral dextrose gel probably leads to higher exclusive breastfeeding after discharge (WHO 2008 definition (yes/no)) compared with control (moderate certainty).

1 finding from 1 review

Turning position vs supine under phototherapy

Rate of decline of serum bilirubin (micromol/L/hr) · term and preterm neonates with hyperbilirubinaemia

Turning position showed no clear difference in rate of fall of serum total bilirubin at 24 hours of starting… compared with supine under phototherapy (low certainty).

1 finding from 1 review

Cuffed vs uncuffed endotracheal tubes

Postextubation stridor Time of measurement: during initial hospitalization · neonates

It is very uncertain whether cuffed (inflated or not) changes postextubation stridor Time of measurement: during initial… compared with uncuffed endotracheal tubes (very low certainty).

1 finding from 1 review

Cuffed vs uncuffed endotracheal tubes

Reintubation for stridor or subglottic stenosis Time of measurement: during initial hospitalization · neonates

It is very uncertain whether cuffed (inflated or not) changes reintubation for stridor or subglottic stenosis Time of measurement:… compared with uncuffed endotracheal tubes (very low certainty).

1 finding from 1 review

Cuffed vs uncuffed endotracheal tubes

Accidental extubation Time of measurement: during initial hospitalization · neonates

It is very uncertain whether cuffed (inflated or not) changes accidental extubation Time of measurement: during initial… compared with uncuffed endotracheal tubes (very low certainty).

1 finding from 1 review