Cochrane · systematic review · CD013736
Cuffed versus uncuffed endotracheal tubes for neonates
Dariya, V, Moresco, L, Bruschettini, M, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Cuffed (inflated or not) compared to uncuffed endotracheal tubes for neonates
Population: neonates
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Postextubation stridor Time of measurement: during initial hospitalization Cuffed (inflated or not) vs uncuffed endotracheal tubes | RR 1.36 [0.35, 5.25] | 1 study · 69 participants | Very low Downgraded: risk of bias, imprecision |
Postextubation subglottic stenosis Time of measurement: during initial hospitalization Cuffed (inflated or not) vs uncuffed endotracheal tubes | no estimate extracted | 1 study · 69 participants | Very low Downgraded: risk of bias, imprecision |
Reintubation for stridor or subglottic stenosis Time of measurement: during initial hospitalization Cuffed (inflated or not) vs uncuffed endotracheal tubes | RR 0.27 [0.01, 6.49] | 1 study · 69 participants | Very low Downgraded: risk of bias, imprecision |
Surgical intervention (e.g. endoscopic balloon dilation, cricoid split, tracheostomy) for stridor or subglottic stenosis Time of measurement: during initial hospitalization Cuffed (inflated or not) vs uncuffed endotracheal tubes | no estimate extracted | 1 study · 69 participants | Very low Downgraded: risk of bias, imprecision |
Reintubation for any reason Cuffed (inflated or not) vs uncuffed endotracheal tubes | RR 0.06 [0.01, 0.45] | 1 study · 69 participants | Very low Downgraded: risk of bias, imprecision |
Accidental extubation Time of measurement: during initial hospitalization Cuffed (inflated or not) vs uncuffed endotracheal tubes | RR 0.82 [0.12, 5.46] | 1 study · 69 participants | Very low Downgraded: risk of bias, imprecision |
All‐cause mortality during initial hospitalization Cuffed (inflated or not) vs uncuffed endotracheal tubes | RR 2.46 [0.1, 58.39] | 1 study · 69 participants | Very low Downgraded: risk of bias, imprecision |