Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

729 questions · 775 findings · 58 reviews · Bone, Joint and Muscle Trauma

No studies found 166 · 21.4%GRADE not reported 24 · 3.1%Very low 356 · 45.9%Low 162 · 20.9%Moderate 47 · 6.1%High 20 · 2.6%

Circular external fixation with limited internal fixation (hybrid fixation) vs standard open reduction internal fixation

Return to activity · adults with tibial plateau fracture (Schatzker types V or VI)

It is very uncertain whether circular external fixation with limited internal fixation (hybrid… changes return to pre‐injury activity level compared with standard open reduction internal fixation (very low certainty).

1 finding from 1 review

Liberal vs restrictive transfusion protocols

Inability to walk 10 feet (3 m; or across a room) without human assistance · Patients with hip fracture repair

Liberal showed no clear difference in inability to walk 10 feet (3 m; or across a room) without human… compared with restrictive threshold transfusion (low certainty).

1 finding from 1 review

Intervention not reported

Patient‐reported functional outcomes (pooled data) · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes patient‐reported functional outcomes (pooled data) (very low certainty).

1 finding from 1 review

Intervention not reported

Need for a secondary/revision operation or substantive physiotherapy for adverse outcomes (e.g. non‐union, malunion or infection) · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes need for a secondary/revision operation or substantive physiotherapy… (very low certainty).

1 finding from 1 review

Intervention not reported

Symptomatic non‐union or malunion, including limping 1 year · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes symptomatic non‐union or malunion, including limping 1 year (very low certainty).

1 finding from 1 review

Intervention not reported

Pain (0 to 40: no pain) · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes pain (0 to 40: no pain) (very low certainty).

1 finding from 1 review

Intervention not reported

Wound complications including superficial/deep wound infection and osteomyelitis 1 year · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes wound complications including superficial/deep wound infection and… (very low certainty).

1 finding from 1 review

Intervention not reported

Fracture union 1 year · individuals more than 18 years old with distal tibial metaphyseal fractures

It is very uncertain whether the intervention changes fracture union 1 year (very low certainty).

1 finding from 1 review

Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)

Pain during activity (short‐term) · patients with patellofemoral pain syndrome (symptoms > 3 weeks (1 study); symptoms > 1 month (3 studies); symptoms > 2 months (2 studies);…

It is very uncertain whether exercise therapy changes pain during activity (short‐term) Scale (0 to 10; higher scores mean… compared with a control strategy (no treatment, placebo or waiting list controls) (very low certainty).

1 finding from 1 review

Supervised exercise therapy vs home exercises

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with patellofemoral pain syndrome (symptoms > 2 months (1 study); not stated (1 study))

It is very uncertain whether supervised exercises changes usual pain (long‐term) VAS (0 to 10; higher scores mean worse pain) compared with home exercises (very low certainty).

2 findings from 1 review

Supervised exercise therapy vs home exercises

Functional ability · patients with patellofemoral pain syndrome (symptoms > 2 months (1 study); not stated (1 study))

It is very uncertain whether supervised exercises changes functional ability (short‐term) AKPS (0 to 100; higher scores mean… compared with home exercises (very low certainty).

2 findings from 1 review