Cochrane · systematic review · CD009699
Red blood cell transfusion for people undergoing hip fracture surgery
Brunskill, SJ, Millette, SL, Shokoohi, A, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Bone, Joint and Muscle TraumaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 6 · 85.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Liberal versus restrictive threshold transfusion for people undergoing hip fracture surgery
Population: people undergoing hip fracture surgery1
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
30‐day mortality Liberal vs restrictive threshold transfusion | RR 0.92 [0.67, 1.26] | 5 studies · 2683 participants | Low Downgraded: risk of bias, imprecision |
Inability to walk 10 feet (3 m; or across a room) without human assistance Liberal vs restrictive threshold transfusion | RR 1 [0.87, 1.15] | 2 studies · 2083 participants | Low Downgraded: risk of bias, imprecision |
Thromboembolism (in hospital) Liberal vs restrictive threshold transfusion | RR 1.15 [0.56, 2.37] | 4 studies · 2416 participants | Low Downgraded: risk of bias, imprecision |
Stroke (in hospital) Liberal vs restrictive threshold transfusion | RR 2.4 [0.85, 6.79] | 4 studies · 2416 participants | Low Downgraded: risk of bias, imprecision |
Wound infection (in hospital) Liberal vs restrictive threshold transfusion | RR 1.61 [0.77, 3.35] | 3 studies · 2332 participants | Low Downgraded: risk of bias, imprecision |
Cardiovascular events ‐ myocardial infarction Liberal vs restrictive threshold transfusion | RR 0.59 [0.36, 0.96] | 3 studies · 2217 participants | Very low Downgraded: risk of bias, imprecision |
Respiratory infections (namely pneumonia) Liberal vs restrictive threshold transfusion | RR 1.35 [0.95, 1.92] | 4 studies · 2416 participants | Low Downgraded: risk of bias, imprecision |