Cochrane · systematic review · CD010387

Exercise for treating patellofemoral pain syndrome

van der Heijden, RA, Lankhorst, NE, van Linschoten, R, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Bone, Joint and Muscle TraumaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
42
current version
GRADE rated
31
No studies
11
Included studies
NR
No studies 11 · 26.2%Ungraded 0 · 0%Very low 31 · 73.8%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Exercise therapy compared with a control strategy (no treatment, placebo or waiting list controls) for patellofemoral pain syndrome

Population: patients with patellofemoral pain syndrome (symptoms > 3 weeks (1 study); symptoms > 1 month (3 studies); symptoms > 2 months (2 studies); symptoms > 3 months (2 studies; symptoms > 6 months (1 study). (Data from a study including participants with patella malalignment are not included here.)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain during activity (short‐term) Scale (0 to 10; higher scores mean worse pain)
Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)
no estimate extracted5 studies · 375 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (short‐term) Scale (0 to 10; higher scores mean worse pain)
Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)
no estimate extracted2 studies · 41 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Pain during activity (long‐term) Scale (0 to 10; higher scores mean worse pain)
Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)
no estimate extracted2 studies · 180 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (long‐term) VAS (0 to 10; higher scores mean worse pain)
Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)
no estimate extracted1 study · 94 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Functional ability (short‐term) Scale (0 to 100; higher scores mean better function)
Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)
SMD 1.1 [0.58, 1.63]7 studies · 483 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Functional ability (long‐term) Scale (0 to 100; higher scores mean better function)
Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)
SMD 1.62 [0.31, 2.94]3 studies · 274 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Recovery (long‐term) Number of patients who had recovered or number of patients no longer troubled by symptoms
Exercise therapy vs a control strategy (no treatment, placebo or waiting list controls)
RR 1.35 [0.99, 1.84]2 studies · 166 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency

Supervised exercises compared with home exercises for patellofemoral pain syndrome

Population: patients with patellofemoral pain syndrome (symptoms > 2 months (1 study); not stated (1 study))
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain during activity (short‐term)
Supervised exercises vs home exercises
no estimate extractedNRNo studies
Usual pain (short‐term) VAS (0 to 10; higher scores mean worse pain)
Supervised exercises vs home exercises
no estimate extracted2 studies · 59 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Pain during activity (long‐term)
Supervised exercises vs home exercises
no estimate extractedNRNo studies
Usual pain (long‐term) VAS (0 to 10; higher scores mean worse pain)
Supervised exercises vs home exercises
no estimate extracted1 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Functional ability (short‐term) AKPS (0 to 100; higher scores mean better function)
Supervised exercises vs home exercises
no estimate extracted1 study · 18 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Functional ability (long‐term) FIQ (number of patients in top (best function) category 13 to 16)
Supervised exercises vs home exercises
RR 1.34 [0.89, 2.03]1 study · 31 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Recovery (long‐term)
Supervised exercises vs home exercises
no estimate extractedNRNo studies

Closed kinetic chain exercises compared with open kinetic chain exercises for patellofemoral pain syndrome

Population: patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not stated (1 study))
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain during activity (short‐term) VAS (0 to 10; higher scores mean worse pain)
Closed kinetic chain exercises vs open kinetic chain exercises
MD 0.032 studies · 90 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (short‐term) VAS (0 to 10; higher scores mean worse pain)
Closed kinetic chain exercises vs open kinetic chain exercises
MD 0.23 studies · 122 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Pain during activity (long‐term) VAS (0 to 10; higher scores mean worse pain)
Closed kinetic chain exercises vs open kinetic chain exercises
MD 2.1 [1.08, 3.12]1 study · 49 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (long‐term) VAS (0 to 10; higher scores mean worse pain)
Closed kinetic chain exercises vs open kinetic chain exercises
MD 0.8 [0.07, 1.53]1 study · 49 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Functional ability (short‐term) AKPS (0 to 100; higher scores mean better function)
Closed kinetic chain exercises vs open kinetic chain exercises
no estimate extracted2 studies · 90 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Functional ability (long‐term) AKPS (0 to 100; higher scores mean better function)
Closed kinetic chain exercises vs open kinetic chain exercises
no estimate extracted1 study · 49 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Recovery (long‐term)
Closed kinetic chain exercises vs open kinetic chain exercises
no estimate extractedNRNo studies

Target of exercise: hip + knee versus knee exercises for treating patellofemoral pain syndrome

Population: patients with patellofemoral pain syndrome (symptoms > 1 month (3 studies); symptoms > 2 months (1 study); symptoms > 3 months (2 studies); not stated (1 study))
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain during activity (short‐term) Scale (0 to 10; higher scores mean worse pain)
Target of exercise: hip + knee vs knee exercises
no estimate extracted3 studies · 104 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (short‐term) VAS (0 to 10; higher scores mean worse pain)
Target of exercise: hip + knee vs knee exercises
no estimate extracted2 studies · 46 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Pain during activity (long‐term) NPRS (0 to 10; higher scores mean worse pain)
Target of exercise: hip + knee vs knee exercises
no estimate extracted1 study · 49 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (long‐term)
Target of exercise: hip + knee vs knee exercises
no estimate extractedNRNo studies
Functional ability (short‐term) Scale (0 to 100; higher scores mean better function)
Target of exercise: hip + knee vs knee exercises
SMD 0.614 studies · 174 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Functional ability (long‐term) Scale (0 to 100; higher scores mean better function)
Target of exercise: hip + knee vs knee exercises
SMD 1.492 studies · 78 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Recovery long‐term Number of patients at least moderately better
Target of exercise: hip + knee vs knee exercises
RR 1.34 [0.93, 1.94]1 study · 29 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency

Target of exercise: hip versus knee exercises for treating patellofemoral pain syndrome

Population: patients with patellofemoral pain syndrome (symptoms > 1 month (1 study); symptoms > 6 months (1 study))
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain during activity (short‐term) VAS (0 to 10; higher scores mean worse pain)
Target of exercise: hip vs knee exercises
no estimate extracted1 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (short‐term)
Target of exercise: hip vs knee exercises
no estimate extractedNRNo studies
Pain during activity (long‐term) VAS (0 to 10; higher scores mean worse pain)
Target of exercise: hip vs knee exercises
no estimate extracted1 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Usual pain (long‐term)
Target of exercise: hip vs knee exercises
no estimate extractedNRNo studies
Functional ability (short‐term) Scale (0 to 100; higher scores mean better function)
Target of exercise: hip vs knee exercises
SMD 0.85 [0.3, 1.4]2 studies · 58 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Functional ability (long‐term) WOMAC (0 to 96; inverted scores so that higher scores mean better function)
Target of exercise: hip vs knee exercises
MD 16.22 [9.17, 23.27]1 study · 36 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Recovery (long‐term)
Target of exercise: hip vs knee exercises
no estimate extractedNRNo studies

High‐intensity versus low‐intensity exercise programmes for patellofemoral pain syndrome

Population: patients with patellofemoral pain syndrome (untreated PFPS of over 2 months in duration)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain during activity (short‐term)
High‐intensity vs low‐intensity exercise programmes
no estimate extractedNRNo studies
Usual pain (short‐term) VAS (0 to 10; higher scores mean worse pain)
High‐intensity vs low‐intensity exercise programmes
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Pain during activity long‐term
High‐intensity vs low‐intensity exercise programmes
no estimate extractedNRNo studies
Usual pain (long‐term) VAS (0 to 10; higher scores mean worse pain)
High‐intensity vs low‐intensity exercise programmes
no estimate extracted1 study · 28 participantsVery low
Downgraded: risk of bias, imprecision
Functional ability (short‐term) FIQ modified (0 to 16; higher scores mean better function)
High‐intensity vs low‐intensity exercise programmes
MD 3.7 [1.59, 5.81]1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Functional ability (long‐term) FIQ modified (0 to 16; higher scores mean better function)
High‐intensity vs low‐intensity exercise programmes
MD 3.9 [1.72, 6.08]1 study · 28 participantsVery low
Downgraded: risk of bias, imprecision
Recovery (long‐term)
High‐intensity vs low‐intensity exercise programmes
no estimate extractedNRNo studies