Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

729 questions · 775 findings · 58 reviews · Bone, Joint and Muscle Trauma

No studies found 166 · 21.4%GRADE not reported 24 · 3.1%Very low 356 · 45.9%Low 162 · 20.9%Moderate 47 · 6.1%High 20 · 2.6%

Ankle brace vs rigid cast

Patient satisfaction: would have preferred the other device · children with acute 'low risk' (undisplaced) ankle fractures

Ankle brace may leads to lower patient satisfaction: would have preferred the other device compared with rigid cast (low certainty).

1 finding from 1 review

Intervention not reported

Subjective knee score ‐ KOOS‐4 score (mean score of 4 components) at 2 years: score from 0 (extreme symptoms) to 100 (no symptoms) · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review

Intervention not reported

Treatment failure (graft rupture or ACL reconstruction) at 2 years5 · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)

The intervention may leads to lower treatment failure (graft rupture or ACL reconstruction) at 2 years5 (low certainty).

1 finding from 1 review

Intervention not reported

Treatment failure (meniscal surgery) at 5 years5,7 · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)

The intervention showed no clear difference in treatment failure (meniscal surgery) at 5 years5,7 (low certainty).

1 finding from 1 review

Intervention not reported

General health‐related quality of life: SF‐36 physical component score (range 0 to 100; higher score = better health state) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
1 finding from 1 review

Intervention not reported

Return to activity or level of sport at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)

The intervention showed no clear difference in return to activity or level of sport at 2 years (low certainty).

1 finding from 1 review

Intramedullary fixation vs open reduction and internal fixation with plate

Function (overall) Various tools · adults (aged ≥ 16 years) with acute middle third clavicle fractures

Intramedullary fixation may leads to higher function or disability (overall) Various tools (Constant score and… compared with open reduction and internal fixation with plate (low certainty).

1 finding from 1 review

Intramedullary fixation vs open reduction and internal fixation with plate

Pain ‐ using the section of Constant score Scale from 0 to 15; with 15 being the best positive score · adults (aged ≥ 16 years) with acute middle third clavicle fractures

It is very uncertain whether intramedullary fixation changes pain ‐ using the section of Constant score Scale from 0 to 15; with… compared with open reduction and internal fixation with plate (very low certainty).

1 finding from 1 review

Intramedullary fixation vs open reduction and internal fixation with plate

Treatment failure (participants who have a non‐routine secondary surgical intervention) ‐ Overall treatment failure · adults (aged ≥ 16 years) with acute middle third clavicle fractures

It is very uncertain whether intramedullary fixation changes treatment failure (participants who have a non‐routine secondary… compared with open reduction and internal fixation with plate (very low certainty).

1 finding from 1 review

Intramedullary fixation vs open reduction and internal fixation with plate

Clinical healing ‐ time to clinical/radiographic fracture consolidation (weeks) · adults (aged ≥ 16 years) with acute middle third clavicle fractures

It is very uncertain whether intramedullary fixation changes clinical healing ‐ time to clinical/radiographic fracture… compared with open reduction and internal fixation with plate (very low certainty).

1 finding from 1 review

Intramedullary fixation vs open reduction and internal fixation with plate

Adverse events ‐ total of adverse events (various: mainly infection; cosmetic result ‐ e.g. prominent metalwork ‐ and symptomatic hardware) · adults (aged ≥ 16 years) with acute middle third clavicle fractures

It is very uncertain whether intramedullary fixation changes adverse events ‐ total of adverse events (various: mainly infection;… compared with open reduction and internal fixation with plate (very low certainty).

1 finding from 1 review

Circular external fixation with limited internal fixation (hybrid fixation) vs standard open reduction internal fixation

Adverse eventse · adults with tibial plateau fracture (Schatzker types V or VI)

It is very uncertain whether circular external fixation with limited internal fixation (hybrid… changes adverse eventse compared with standard open reduction internal fixation (very low certainty).

1 finding from 1 review