Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Anticipated high responders: higher vs lower dose of FSH

IU vs 100 IU · women undergoing IVF/ICSI who are anticipated to have a hyper‐response to stimulation based on at least one ORT measure

Anticipated high responders: higher showed no clear difference in IU vs 100 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated low‐responders: higher vs lower dose of FSH

300/450 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in 300/450 IU vs 150 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated low‐responders: higher vs lower dose of FSH

400/450 IU vs 300 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in 400/450 IU vs 300 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated low‐responders: higher vs lower dose of FSH

IU vs 450 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in IU vs 450 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated normal responders: higher vs lower dose of FSH

IU vs 100 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in IU vs 100 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated normal responders: higher vs lower dose of FSH

225/200 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in 225/200 IU vs 150 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated normal responders: higher vs lower dose of FSH

IU vs 225 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure

Anticipated normal responders: higher showed no clear difference in IU vs 225 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Intrauterine infusion of autologous platelet‐rich plasma vs no intervention

Live birth or ongoing pregnancy · women undergoing assisted reproduction

It is very uncertain whether intrauterine injection of autologous platelet‐rich plasma changes live birth (or ongoing pregnancy) compared with no intervention (very low certainty).

1 finding from 1 review

Intrauterine infusion/injection of autologous platelet‐rich plasma vs placebo or no intervention

Adverse events: preterm delivery · women undergoing assisted reproduction

Intrauterine infusion/injection of autologous platelet‐rich plasma may leads to higher adverse events: preterm delivery compared with no intervention or placebo (low certainty).

1 finding from 1 review

Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor

Live birth or ongoing pregnancy · women undergoing assisted reproduction

It is very uncertain whether intrauterine infusion of autologous platelet‐rich plasma changes live birth (or ongoing pregnancy compared with intrauterine infusion of granulocyte colony‐stimulating factor (very low certainty).

1 finding from 1 review

Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor

Miscarriage · women undergoing assisted reproduction

It is very uncertain whether intrauterine infusion of autologous platelet‐rich plasma changes miscarriage compared with intrauterine infusion of granulocyte colony‐stimulating factor (very low certainty).

1 finding from 1 review

Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor

Clinical pregnancy · women undergoing assisted reproduction

It is very uncertain whether intrauterine infusion of autologous platelet‐rich plasma changes clinical pregnancy compared with intrauterine infusion of granulocyte colony‐stimulating factor (very low certainty).

1 finding from 1 review