Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,252 questions · 2,353 findings · 210 reviews · Neonatal

No studies found 432 · 18.4%GRADE not reported 99 · 4.2%Very low 609 · 25.9%Low 737 · 31.3%Moderate 385 · 16.4%High 91 · 3.9%

Two per cent CHG vs alcohol hand sanitiser (61% alcohol and emollients)

Incidence of bacteriologically confirmed infection (types of infection as specified by study authors) within the first 28 days of life ‐ all infections · Neonates and caregivers

Two per cent CHG probably leads to lower incidence of bacteriologically confirmed infections (types of… compared with alcohol hand sanitiser (61% alcohol and emollients) (moderate certainty).

1 finding from 1 review

Alcohol‐based handrub vs usual care

Incidence of (study author‐defined) suspected infection within the first 28 days of life · Neonates and caregivers

It is very uncertain whether alcohol‐based handrub changes incidence of suspected infections (author‐defined) within the first… compared with usual care (very low certainty).

1 finding from 1 review

Four per cent chlorhexidine + hand hygiene promotion vs usual care

Authors reported adverse outcomes (events without hospitalisation) · Neonates and caregivers

It is very uncertain whether four per cent chlorhexidine + hand hygiene promotion changes authors reported adverse outcomes (events without hospitalisation) compared with usual care (very low certainty).

1 finding from 1 review