Severe dialysis dysequilibrium syndrome · patients requiring haemodialysis
It is very uncertain whether summary of findings table ‐ High sodium dialysate changes severe dialysis dysequilibrium syndrome compared with standard sodium dialysate (very low certainty).
1 finding from 1 review
Death · patients requiring haemodialysis
1 finding from 1 review
Adverse events · patients requiring haemodialysis
It is very uncertain whether summary of findings table ‐ High sodium dialysate changes adverse events compared with standard sodium dialysate (very low certainty).
1 finding from 1 review
Death (all causes) · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors leads to lower all‐cause death median compared with placebo (high certainty).
3P‐MACE median · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors probably leads to lower 3P‐MACE median compared with placebo (moderate certainty).
1 finding from 1 review
4P‐MACE median · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors probably leads to lower 4P‐MACE median compared with placebo (moderate certainty).
1 finding from 1 review
Kidney composite outcome median · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors leads to lower kidney composite outcome median compared with placebo (high certainty).
1 finding from 1 review
Kidney failure · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors leads to lower kidney failure median compared with placebo (high certainty).
1 finding from 1 review
Hypoglycaemia requiring third‐party assistance median · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors leads to lower hypoglycaemia requiring third‐party assistance median compared with placebo (high certainty).
1 finding from 1 review
Diabetic ketoacidosis median · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors probably leads to higher diabetic ketoacidosis median compared with placebo (moderate certainty).
1 finding from 1 review
Virologically confirmed dengue case incidence (any severity, any phenotype) · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Prevalence of DENV infection (any severity, any phenotype)a · children and adults at risk of dengue infection
wMel‐Wolbachia infected Aedes aegypti deployments probably leads to lower prevalence of DENV infection (any severity, any phenotype)a compared with no deployments (moderate certainty).
1 finding from 1 review
OR 0.23 [0.15, 0.35]
6306 participants
Moderate
Prevalence of dengue RNA in the mosquito population · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mosquito density (for population suppression strategy) · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Prevalence of Wolbachia‐carrying mosquitoes (for population replacement strategy) · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events potentially related to Wolbachia‐carrying Aedes deployments · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Difference between effect estimates from RCTs and observational studies [for RCTs vs OBSs] · systematic reviews and overviews of systematic reviews
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Sensitivity · Children and adults with primary or permanent dentition undergoing dental caries assessment
Across 13 studies, the sensitivity of teledentistry (photographic) caries diagnosis versus visual examination ranged from 48% to 98.3%; the review pooled no estimate and did not grade certainty.
1 finding from 1 review
Association between orthodontic treatment duration and ICLs incidence · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new ICLs
ICLs incidence increased with longer orthodontic treatment duration (meta-regression P<.01; ungraded).
1 finding from 1 review
Dental caries in children · Children and/or adolescents (<18 years) without background systemic disease
Probiotics probably make little to no difference to the number of dental caries versus control (MD -0.24 carious pieces, 95%CI -0.72 to 0.23; low certainty).
1 finding from 1 review