Cochrane · systematic review · CD015526

Interventions for preventing haemodialysis dysequilibrium syndrome

Kulkarni, M, Prabhu, AR, Rao, IR, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library

Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
8
No studies
2
Included studies
NR
No studies 2 · 20%Ungraded 0 · 0%Very low 5 · 50%Low 3 · 30%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table ‐ Sodium modelling compared to slow dialysis for haemodialysis patients

Population: haemodialysis patients
5 questions
OutcomeEffectEvidenceStatus / GRADE
Dialysis dysequilibrium syndrome
Summary of findings table ‐ Sodium modelling vs slow dialysis
no estimate extracted1 study · 15 participantsLow
Downgraded: imprecision, publication bias
Severe dialysis dysequilibrium syndrome
Summary of findings table ‐ Sodium modelling vs slow dialysis
no estimate extracted1 study · 15 participantsLow
Downgraded: imprecision, publication bias
Death
Summary of findings table ‐ Sodium modelling vs slow dialysis
no estimate extracted1 study · 15 participantsLow
Downgraded: imprecision, publication bias
Adverse events
Summary of findings table ‐ Sodium modelling vs slow dialysis
RR 1.33 [0.15, 11.64]1 study · 15 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Duration of hospital stay ‐ not reported
Summary of findings table ‐ Sodium modelling vs slow dialysis
no estimate extractedNRNo studies

Summary of findings table ‐ High sodium dialysate compared to standard sodium dialysate for haemodialysis patients

Population: haemodialysis patients
5 questions
OutcomeEffectEvidenceStatus / GRADE
Dialysis dysequilibrium syndrome
Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate
RR 0.07 [0, 1.12]1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Severe dialysis dysequilibrium syndrome
Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate
RR 0.47 [0.02, 10.32]1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Death
Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate
RR 0.29 [0.08, 1.02]1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Duration of hospital stay ‐ not reported
Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate
no estimate extractedNRNo studies