Cochrane · systematic review · MR000034
Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials: a meta‐epidemiological study
Toews, I, Anglemyer, A, Nyirenda, JLZ, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
MethodologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
1
current version
GRADE rated
1
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings
Population: systematic reviews and overviews of systematic reviews
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Difference between effect estimates from RCTs and observational studies [for RCTs vs OBSs] | no estimate extracted | NR | Low Downgraded: risk of bias, inconsistency |