Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Treatment success (caries lesion arrest or restoration survival) · Children with dentin caries lesions in the outer half of dentin on occlusal surfaces of primary teeth
Conventional restorative treatment with resin composite gave a higher treatment success rate than resin sealing for outer-half occlusal dentin caries in primary teeth (2 studies; low certainty).
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Low-level laser therapy (LLLT) + calcium hydroxide showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Metapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with zinc oxide and propolis (ZOP); GRADE not reported.
1 finding from 1 review
Postoperative sensitivity · People with permanent posterior teeth restored with class I or II direct restorations
Postoperative sensitivity at 12 months did not differ significantly between low polymerization shrinkage and methacrylate composites (OR 1.65, 95% CI 0.71 to 3.81; Moderate certainty).
2 findings from 1 review
Specificity for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the meta-analysis tailored to Germany, pooled specificity of visual detection for advanced occlusal caries was 96.5% (95% CI 95 to 97) (ungraded).
3 findings from 1 review
Specificity 96.5 [95, 97]
50 studies
GRADE not reported
Specificity 90.9 [88, 93]
94 studies
GRADE not reported
Specificity 84.9 [82, 89]
55 studies
GRADE not reported
Caries increment in permanent teeth · Children or adolescents
The NMR reported a difference between fluoride in gel and placebo at randomisation years 1954 to 1980; no GRADE assessment was reported.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Low-level laser therapy (LLLT) showed no clear difference in radiological failure compared with low-level laser therapy (LLLT) + calcium hydroxide; GRADE not reported.
1 finding from 1 review
PPV for detecting all (initial and advanced) occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the German private-practice setting, the positive predictive value of radiographic detection for all (initial and advanced) occlusal caries was 22.6% at an assumed prevalence of 11.0% (ungraded).
2 findings from 1 review
PPV 22.6
9 studies
GRADE not reported
PPV 32.1
11 studies
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Diode laser + mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with formocresol (FC) + zinc oxide and eugenol (ZOE); GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Mineral trioxide aggregate (MTA) probably leads to lower clinical failure compared with calcium hydroxide (CH) (moderate certainty).
2 findings from 1 review
RR 0.16 [0.04, 0.70]
4 studies · 150 participants
Moderate
No clinical failure in any participant (Tuna 2008); not estimable (direct pulp capping)
1 study · 50 participants
GRADE not reported
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
It is very uncertain whether calcium hydroxide cement (Dycal) changes clinical failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
Zinc oxide and eugenol (ZOE) led to lower clinical failure compared with ZOE + calcium hydroxide + iodoform (unnamed product); GRADE not reported.
1 finding from 1 review
NPV for detecting advanced occlusal caries · Occlusal surfaces of permanent molars (demonstrated in 12-14 year-olds; underlying diagnostic accuracy studies, mostly in vitro)
In the German private-practice setting, the negative predictive value of visual detection for advanced occlusal caries was 85.9% at an assumed prevalence of 22.0% (ungraded).
2 findings from 1 review
NPV 85.9
50 studies
GRADE not reported
NPV 97.5
55 studies
GRADE not reported
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Calcium hydroxide (CH) led to higher radiological failure compared with portland cement (PC); GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Biodentine showed no clear difference in radiological failure compared with propolis; GRADE not reported.
1 finding from 1 review
Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
Vitapex (calcium hydroxide/iodoform) showed no clear difference in radiological failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline); GRADE not reported.
1 finding from 1 review
Dental caries · Children and adolescents (general population, aged under 20 years)
In children and adolescents, passive tobacco exposure (prenatal or postnatal) is associated with higher odds of dental caries (pooled OR 1.53, 95% CI 1.39 to 1.68; 21 studies), though heterogeneity was high (I2=86.5%); certainty of evidence not graded.
1 finding from 1 review