Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,317 questions · 75,239 findings · 5,342 reviews

No studies found 15,213 · 20.2%GRADE not reported 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

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Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Quality of life · adults with biliary sphincter of Oddi dysfunction
2 findings from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation

Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants with ≥ 1 serious adverse events at 1 year compared with endoscopic papillary balloon dilation (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

All‐cause mortality · farmworkers, soldiers, and people in endemic areas

Summary of findings table ‐ Antibiotics showed no clear difference in all‐cause mortality compared with placebo or no intervention (low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Clinical diagnosis of leptospirosis regardless of laboratory confirmation · farmworkers

It is very uncertain whether summary of findings table ‐ Antibiotics changes clinical diagnosis of leptospirosis regardless of laboratory… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Laboratory‐confirmed leptospirosis · farmworkers

It is very uncertain whether summary of findings table ‐ Antibiotics changes clinical diagnosis of leptospirosis confirmed by laboratory diagnosis compared with other antibiotics (very low certainty).

2 findings from 1 review

Antibiotics vs other antibiotics

Non‐serious adverse events · farmworkers

It is very uncertain whether summary of findings table ‐ Antibiotics changes non‐serious adverse events compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

Laboratory‐confirmed leptospirosis · farmworkers, soldiers, and people in endemic areas

It is very uncertain whether summary of findings table ‐ Antibiotics changes laboratory‐confirmed leptospirosis compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

Clinical diagnosis of infection regardless of laboratory confirmed · farmworkers, soldiers, and people in endemic areas

Summary of findings table ‐ Antibiotics showed no clear difference in clinical diagnosis of infection regardless of laboratory confirmed compared with placebo or no intervention (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

Clinical diagnosis confirmed by laboratory diagnosis · farmworkers, soldiers, and people in endemic areas

Summary of findings table ‐ Antibiotics showed no clear difference in clinical diagnosis confirmed by laboratory diagnosis compared with placebo or no intervention (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

Non‐serious adverse events · farmworkers, soldiers, and people in endemic areas

It is very uncertain whether summary of findings table ‐ Antibiotics changes non‐serious adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no intervention

All‐cause mortality · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality compared with placebo or no intervention (very low certainty).

1 finding from 1 review