Proportion of people requiring non‐invasive ventilation · acute exacerbations of chronic obstructive pulmonary disease
It is very uncertain whether intravenous magnesium sulfate + standard care changes proportion of people requiring non‐invasive ventilation compared with placebo + standard care (very low certainty).
1 finding from 1 review
Change in oxygen saturation (SaO2) · acute exacerbations of chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in dyspnoea score · acute exacerbations of chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
FEV1 · acute exacerbations of chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of people with serious adverse events · acute exacerbations of chronic obstructive pulmonary disease
1 finding from 1 review
Length of hospital stay · acute exacerbations of chronic obstructive pulmonary disease
1 finding from 1 review
Change in oxygen saturation (SaO2) · acute exacerbations of chronic obstructive pulmonary disease
1 finding from 1 review
Change in dyspnoea score · acute exacerbations of chronic obstructive pulmonary disease
1 finding from 1 review
Lung function: FEV1 mL (change from baseline) · acute exacerbations of chronic obstructive pulmonary disease
1 finding from 1 review
Proportion of people with hospital admissions (from the emergency room) · acute exacerbations of chronic obstructive pulmonary disease
It is very uncertain whether nebulised magnesium sulfate + standard care changes proportion of people with hospital admissions (from the emergency… compared with placebo + standard care (very low certainty).
1 finding from 1 review
Incidence of admissions to the ICU · acute exacerbations of chronic obstructive pulmonary disease
It is very uncertain whether nebulised magnesium sulfate + standard care changes proportion of people requiring ICU admission compared with placebo + standard care (very low certainty).
1 finding from 1 review
Intervention not reported
Total studies: 8 RCTs Total Participants: 9983 · Adolescents and adults with symptomatic asthma Interventions: HD‐ICS/LABA, MD‐TRIPLE, HD‐TRIPLE Comparator (reference): Medium‐Dose…
1 finding from 1 review
Intervention not reported
Severe exacerbations ‐ MD TRIPLE vs HD‐ICS/LABA№ of participants: 812(1 RCT)
The intervention showed no clear difference in severe exacerbations ‐ MD TRIPLE vs HD‐ICS/LABA№ of participants:… (low certainty).
1 finding from 1 review
Intervention not reported
ACQ responders at 6 months ‐ MD TRIPLE vs MD‐ICS/LABA№ of participants: 3063(3 RCTs)
The intervention showed no clear difference in ACQ responders at 6 months ‐ MD TRIPLE vs MD‐ICS/LABA№ of… (low certainty).
1 finding from 1 review
Intervention not reported
ACQ responders at 6 months ‐ HD TRIPLE vs MD‐ICS/LABA№ of participants: 1916(2 RCTs)
It is very uncertain whether the intervention changes ACQ responders at 6 months ‐ HD TRIPLE vs MD‐ICS/LABA№ of… (very low certainty).
1 finding from 1 review
Intervention not reported
ACQ responders at 6 months ‐ MD TRIPLE vs HD‐ICS/LABA№ of participants: 2480(2 RCTs)
The intervention showed no clear difference in ACQ responders at 6 months ‐ MD TRIPLE vs HD‐ICS/LABA№ of… (moderate certainty).
1 finding from 1 review
Intervention not reported
ACQ responders at 6 months ‐ HD TRIPLE vs HD‐ICS/LABA№ of participants: 4818(4 RCTs)
The intervention probably leads to higher ACQ responders at 6 months ‐ HD TRIPLE vs HD‐ICS/LABA№ of… (moderate certainty).
1 finding from 1 review
Intervention not reported
ACQ responders at 6 months ‐ HD TRIPLE vs MD TRIPLE№ of participants: 2821(3 RCTs)
The intervention showed no clear difference in ACQ responders at 6 months ‐ HD TRIPLE vs MD TRIPLE№ of… (moderate certainty).
1 finding from 1 review
Intervention not reported
ACQ responders at 6 months ‐ TRIPLE vs DUAL№ of participants: 7881(5 RCTs)
The intervention may leads to higher ACQ responders at 6 months ‐ TRIPLE vs DUAL№ of participants: 7881(5… (low certainty).
1 finding from 1 review
Intervention not reported
ACQ responders at 12 months ‐ HD‐ICS/LABA vs MD‐ICS/LABA№ of participants: 2817(2 RCTs)
The intervention showed no clear difference in ACQ responders at 12 months ‐ HD‐ICS/LABA vs MD‐ICS/LABA№ of… (low certainty).
1 finding from 1 review